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Acknowledgments

Reproductive and developmental toxicity

Some pesticides are known to cause birth defects or interfere with normal development. Weight-of-the-evidence evaluations of this type of toxicity have been conducted by the State of California and by the U.S. EPA under its Toxics Release Inventory program. Many pesticides that disrupt endocrine functions also cause reproductive and developmental harm, as well as other adverse effects. The absence of a chemical on any of these lists does not necessarily mean it is not a reproductive or developmental toxicant. It may mean that it has not yet been evaluated.

pesticides bulletCalifornia Proposition 65 List
pesticides bulletU.S. EPA Toxics Release Inventory List


California Proposition 65 List

Pesticides determined by the state of California to cause reproductive and developmental harm, e.g., birth defects, infertility, sterility and impairment of normal growth and development. A list of chemicals "known to the State to cause reproductive and developmental toxicity" is maintained by the State of California under the Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65).

The absence of a chemical on this list does not necessarily mean it is not a reproductive or developmental toxicant. It may mean that it has not yet been evaluated by the agencies responsible. More detail is given in the "About the Data" section.

About the Data

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U.S. EPA Toxics Release Inventory List

In 1986, Congress passed the Emergency Planning and Community Right-To-Know Act (EPCRA) and the Pollution Prevention Act (PPA), with the intent of increasing the transparency of the use and disposal of chemicals in manufacturing, mining, and other activities. Section 313 of the EPCRA and section 6607 of the PPA required companies that release toxic materials to provide information to U.S. EPA on the identity and amounts of these toxic chemicals they are releasing to air, land and water. This information is made available to the public through U.S. EPA as the Toxics Release Inventory (TRI), providing valuable information on the release and transport of toxic chemicals in the U.S.

U.S. EPA publishes a list of chemicals that must be reported. A chemical is placed on the list if it is toxic to humans or damaging to the environment. The current TRI toxic chemical list contains approximately 650 individually listed chemicals and 30 chemical groups. Of this group, only 350 individual chemicals and 25 chemical groups are pesticides or related compounds. Of these pesticide chemicals, only 222 have been formally ranked through the TRI program for their toxicity.

Toxicity categories evaluated for the TRI list of chemicals includes acute toxicity, carcinogenicity, reproductive and developmental toxicity, environmental toxicity and toxicity to organ systems including cardiovascular, liver, gastrointestinal, kidney, immune, hematological, and respiratory systems.

Environmental Defense maintains a web site called Scorecard, at which you can find information on the TRI chemicals being released in your neighborhood, with a map showing the location of the responsible facilities.

References:

  1. Toxics Release Inventory and Community Right to Know, U.S. EPA. Viewed on June 13, 2005.
  2. What is the Toxics Release Inventory?, U.S. EPA, Viewed on June 13, 2005.
  3. Hazard Information on Toxic Chemicals Added to EPCRA Section 313 Under Chemical Expansion, U.S. EPA, Viewed on June 13, 2005.

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Last updated June 13, 2005 .


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