PAN Pesticides Database - Chemicals

Methoxychlor - Identification, toxicity, use, water pollution potential, ecological toxicity and regulatory information

Note: See Working with the Information on this Page section below for important notes about this data.

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Identifying information, including synonyms, ID numbers, use type, chemical classification, a link to a list of all products containing this chemical and a list of the top crops this pesticide is used on in California.
Signs and symptoms of poisoning, first aid, and links to treatment information for this chemical.
Link to information on toxicity to humans, including carcinogenicity, reproductive and developmental toxicity, neurotoxicity, and acute toxicity.
Links to world-wide registration status as well as regulatory information for the U.S. and California.
Water quality standards and physical properties affecting water contamination potential.
Toxicity to aquatic organisms.
List of chemicals in the same family, including breakdown products, salts, esters, isomers, and other derivatives.
 

Chemical Identification and Use for Methoxychlor

Basic Identification Information About This Chemical
Chemical Name: Methoxychlor
CAS Number: 72-43-5 (p,p'-Methoxychlor)
30667-99-3 (o,p'-Methoxychlor)
U.S. EPA PC Code: 034001
CA DPR Chem Code: 384
Molecular Weight: 345.66
Molecular Structure:
Use Type: Insecticide
Chem Class: Organochlorine
View Related Chemicals
 
Additional Resources About This Chemical Class and Use Type
 
Other Names for this Chemical
About Chemical Synonyms
(US EPA PC Code ) , 034001 (US EPA PC Code Text ) , 1,1'-(2,2,2-Trichloroethylidene)bis[4-methoxybenzene] , 1,1,1-Trichloro-2,2-bis(p-anisyl)ethane , 2,2-Bis(p-anisyl)-1,1,1-trichloroethane , 2,2-bis(p-Methoxyphenyl)-1,1,1-trichloroethane , 2,2-Bis(p-methoxyphenyl)-1,1,1-trichloroethane 88% and related compounds 12% , 275 (PDP Code) , 30667-99-3 (CAS number) , 30667993 (CAS number without hyphens) , 384 (CA DPR Chem Code) ) , 72-43-5 (CAS number) , 72435 , 72435 (CAS number without hyphens) , Benzene, 1,1'-(2,2,2-trichloroethylidene)bis(4-methoxy)- , Chemform Methoxychlor , Dianisyl trichloroethane , Dimethoxydiphenyltrichloroethane , ENT 1716 , Marlate , Methoxcide , Methoxychlor , Methoxychlor ( 2,2-bis(p-methoxyphenyl)-1,1,1-trichloroethane ) , METHOXYCHLOR (CA DPR Chem Code Text ) , Methoxychlor p,p' , Methoxychlor [Benzene, 1,1'-(2,2,2-trichloroethylidene)bis [4-methoxy-]] , Methoxychlore , Metoxicloro , NCI-C00497 , OMS 466 , OMS-466 , p,p'-(Dimethoxydiphenyl)trichloroethane , p,p'-DMDT
 
Products Containing This Chemical
Current and historic U.S. registered products
View U.S. Products All Products Currently Registered Products
 

Signs and Symptoms of Methoxychlor Poisoning

NOTE! There may be other diseases and chemicals that have similar symptoms.

If you have a poisoning emergency in the United States call 1-800-222-1222.
If the victim has collapsed or is unconscious, call 911.

Methoxychlor is a Organochlorine compound.

Report a Poisoning

Symptoms of Poisoning with Organochlorine Compounds
Find Products Containing this Chemical

- Hypersensitive to stimulation, sensation of prickling, tingling or creeping on skin.
- Headache, dizziness, nausea, vomiting, incoordination, tremor, mental confusion, hyperexcitable state.
- In severe cases: convulsions, seizures, coma and respiratory depression.

Source for Group Symptoms: Recognition and Management of Pesticide Poisoning, 5th edition, U.S. EPA, Chapter 6.

Treatment for Organochlorine Poisoning

See: Recognition and Management of Pesticide Poisoning, 5th edition, U.S. EPA, Chapter 6, page 58.

 
Symptoms of Methoxychlor Exposure from the International Chemical Safety Cards (ICSC)

Report a Poisoning

View full ICSC Cards: English   Español   Française   Chinese   Dutch   Finnish   German   Hungarian   Japanese   Swahili   Thai   Urdu  
NOTE! PREVENT DISPERSION OF DUST! STRICT HYGIENE! AVOID EXPOSURE OF (PREGNANT) WOMEN!

Route of Exposure

Symptoms

First Aid

Inhalation (See Ingestion). Fresh air rest.
Skin Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes First rinse with plenty of water for several minutes (remove contact lenses if easily possible) then take to a doctor.
Ingestion Convulsions. Diarrhoea. Nausea. Vomiting. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Give plenty of water to drink. Refer for medical attention.
Notes for ICSC Information
Temperature of decomposition unknown in literature. Depending on the degree of exposure periodic medical examination is indicated. If the substance is formulated with solvent(s) also consult the card(s) (ICSC) of the solvent(s). Carrier solvents used in commercial formulations may change physical and toxicological properties. Maralate Marlate Metox Prentox Methoxicide are trade names. Also consult ICSC 0034 for DDT.
 

Toxicity Information for Methoxychlor

  Note: Information for many chemicals is incomplete and may not be fully representative of effects on humans. Why?

Summary Toxicity Information

PAN Bad Actor
Chemical
1
Acute
Toxicity
2
Carcinogen Cholinesterase
Inhibitor
Ground
Water Contaminant
Developmental or
Reproductive Toxin
Endocrine
Disruptor
Not Listed Slight Unclassifiable No
Suspected
 
Indicates high toxicity in the given toxicological category. Indicates no available weight-of-the-evidence summary assessment. For additional information on toxicity from scientific journals or registration documents, see the "Additional Resources for Toxicity " section of the chemical detail page.
1. PAN Bad Actors are chemicals that are one or more of the following: highly acutely toxic, cholinesterase inhibitor, known/probable carcinogen, known groundwater pollutant or known reproductive or developmental toxicant. NOTE! Because there are no authoritative lists of Endocrine Disrupting (ED) chemicals, EDs are not yet considered PAN Bad Actor chemicals.
2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.

Detailed Toxicity Information

Acute Toxicity 2
Methoxychlor
WHO Acute Hazard
TRI Acute Hazard
Material Safety Data Sheets
Acute rating from U.S. EPA product label
U.S. NTP Acute Toxicity Studies
      View Studies
Cholinesterase Inhibitor
U, Unlikely to be Hazardous
Not Listed
Not Available
Slightly Toxic
Slightly Toxic

No
2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.
 
Cancer Information
Methoxychlor
IARC Carcinogens
U.S. NTP Carcinogens
California Prop 65 Known Carcinogens
U.S. EPA Carcinogens
TRI Carcinogen
3, Unclassifiable
Not Listed
Not Listed
D, Unclassifiable, insufficient data
Not Listed
 
Endocrine Disruption
Methoxychlor
Illinois EPA list
Keith list
Colborn list
Benbrook list
Danish Inert list
EU list
Known
Yes
Yes
Yes
Not listed
Yes
 
Reproductive and Developmental Toxicity
Methoxychlor
CA Prop 65 Developmental Toxin
U.S. TRI Developmental Toxin
CA Prop 65 Female Reproductive Toxin
CA Prop 65 Male Reproductive Toxin
U.S. TRI Reproductive Toxin
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
 
Chemicals of Special Concern
Methoxychlor
PAN Bad Actors
PAN Dirty Dozen list
Not Listed
Not Listed
 

Water Pollution Potential and Criteria for Methoxychlor

Water Pollution Potential

PAN Ground Water Contaminant Rating Insufficient Data
 
Physical Property Data Related to Water Contamination Potential
Water Solubility (Avg, mg/L)
Adsorption Coefficient (Koc)
Hydrolysis Half-life (Avg, Days)
Aerobic Soil Half-life (Avg, Days)
Anaerobic Soil Half-life (Avg, Days)
0.10
80,000
-
120.0
-
 
 

Water Standards and Criteria

U.S. National Drinking Water Standards and Health Criteria
g/L unless noted  
Maximum Contaminant Level (MCL) 40.0  
Maximum Contaminant Level Goal (MCLG) 40.0  
One Day Exposure Health Advisory Level 50.0  
Ten Day Exposure Health Advisory Level 50.0  
Lifetime Exposure Health Advisory Level 40.0  
Reference Dose 5.00 (g/kg/day)  
U.S. Drinking Water Equivalent Level 200.0  
Concentration with Lifetime Cancer Risk of 1 in 10,000  
Canada Drinking Water Standards and Criteria
g/L unless noted  
Maximum Acceptable Concentration (MAC) 900.0
Interim Maximum Acceptable Concentration (IMAC)
Aesthetic Objectives
WHO Water Quality Criteria
Concentration (μg/l unless otherwise noted) 20.0
 

Regulatory Information for Methoxychlor

International Regulatory Status

 
UNEP Persistent Organic Pollutant (POP)
UNEP Prior Informed Consent Chemical (PIC)
WHO Obsolete Pesticide
Not Listed
Not Listed
Not Listed
 

U.S. and California Regulatory Status

U.S. EPA Registered
U.S. EPA Hazardous Air Pollutant
U.S. EPA Minimum Risk Pesticide (25b list)

CA Registered
CA Groundwater Contaminant
CA Toxic Air Contaminant
No
Yes
No

No
Not Listed
HAPTAC, Pesti
 

Maximum Tolerance and Residue Levels

Codex Alimentarius
   (UN FAO Maximum Residue Limits)
U.S. Maximum Tolerance Levels
European Union Maximum Residue Levels
Go to web site

Go to web site

Go to web site
 

Ecotoxicity for Methoxychlor

Note! Information for many chemicals is incomplete and may not be fully representative of effects on the environment. Why? Click on underlined terms for definitions and additional information.

Aquatic Ecotoxicity

All Toxic Effects for Organism Group
Organism Group Effects Noted
Amphibians Behavior, Development, Growth, Mortality
Annelida Mortality
AquaticPlants Accumulation
Crustaceans Accumulation, Behavior, Biochemistry, Development, Enzyme(s), Growth, Intoxication, Mortality, No Effect Coded, Physiology, Population
Echinoderms Behavior, Biochemistry, Development, Growth, Histology, Morphology, Mortality
Fish Accumulation, Behavior, Biochemistry, Cell(s), Development, Enzyme(s), Genetics, Growth, Histology, Hormone(s), Intoxication, Morphology, Mortality, No Effect Coded, Physiology, Population, Reproduction
Insects Accumulation, Behavior, Development, Ecosystem Process, Intoxication, Mortality, Population
Molluscs Accumulation, Behavior, Biochemistry, Development, Enzyme(s), Growth, Morphology, Mortality
NematodesandFlatworms Population
Phytoplankton Accumulation, Biochemistry, Physiology, Population
Zooplankton Accumulation, Behavior, Intoxication, Mortality, No Effect Coded, Population, Reproduction
~ Un-Assigned Accumulation, Mortality, Population
View All Aquatic Ecotoxicity Studies and References
 
Summary of Acute Toxicity for Organism Group
Organism Group Average Acute Toxicity Acute Toxicity Range
Amphibians Highly Toxic Highly Toxic
Annelida Highly Toxic Highly Toxic
Crustaceans Very Highly Toxic Very Highly Toxic
Fish Highly Toxic Moderate to Very High Toxicity
Insects Very Highly Toxic Very Highly Toxic
Molluscs Moderately Toxic Moderate to High Toxicity
Zooplankton Very Highly Toxic Very Highly Toxic
~ Un-Assigned Very Highly Toxic Very Highly Toxic
View All Acute Summaries
 

Terrestrial Ecotoxicity

Summary of Acute Toxicity for Organism Group
Organism Group Average Acute Toxicity Acute Toxicity Range
HoneybeesSlightly ToxicSlightly Toxic
Note: Population-level effects on honeybees may occur even if a pesticide has low acute toxicity. For example, certain pesticides interfere with honeybee reproduction, ability to navigate, or temperature regulation, any of which can have an effect on long-term survival of honeybee colonies. The neonicotinoids, pyrethroids and keto-enol pesticides are some types of pesticides causing one or more of these effects.
Honeybee Chronic Toxicity

Sorry, no honeybee chronic toxicity data available for this chemical. Try related chemicals.

Related Chemicals for Methoxychlor

CAS Number Relation Reason Chemical Name Chem Detail Symptoms California Use Chem Use Type U.S. EPA Reg PAN Bad Actor
72-43-5, 30667-99-3 Parent P Methoxychlor View View View Insecticide No Not Listed
65148-80-3 Related 5a,6 3-MeO-o,p'-DDE View View View No Not Listed
65148-81-4 Related 5a,6 4-MeO-o,p'-DDE View View View No Not Listed
65148-72-3 Related 6 4-MeO-o,p'-DDT View View View No Not Listed
65148-75-6 Related 5a,6 5-MeO-o,p'-DDD View View View No Not Listed
65148-82-5 Related 5a,6 5-MeO-o,p'-DDE View View View No Not Listed
65148-74-5 Related 6 5-MeO-o,p'-DDT View View View No Not Listed
Related 5a Methoxychlor olefin View View View Breakdown product No Not Listed
Related 13 Methoxychlor Total View View View No Not Listed
Related 8 Methoxychlor, other related View View View Insecticide No Not Listed
 
Working with the Information on this Page

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* Data marked with an asterisk indicates that this chemical is not explicitly listed on the corresponding list. Instead, it belongs to a group of chemicals that IS designated on the list. For example, if an agency assigns a classification of reproductive toxicant to "mercury compounds", that classification is applied to all mercury compounds in the PAN Pesticide database, which are then marked with an asterisk.

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