PAN Pesticides Database - Chemicals

Piperonyl butoxide - Identification, toxicity, use, water pollution potential, ecological toxicity and regulatory information

Note: See Working with the Information on this Page section below for important notes about this data.

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Identifying information, including synonyms, ID numbers, use type, chemical classification, a link to a list of all products containing this chemical and a list of the top crops this pesticide is used on in California.
Signs and symptoms of poisoning, first aid, and links to treatment information for this chemical.
Link to information on toxicity to humans, including carcinogenicity, reproductive and developmental toxicity, neurotoxicity, and acute toxicity.
Links to world-wide registration status as well as regulatory information for the U.S. and California.
Water quality standards and physical properties affecting water contamination potential.
Toxicity to aquatic organisms.
List of chemicals in the same family, including breakdown products, salts, esters, isomers, and other derivatives.
 

Chemical Identification and Use for Piperonyl butoxide

Basic Identification Information About This Chemical
Chemical Name: Piperonyl butoxide
CAS Number: 51-03-6
U.S. EPA PC Code: 067501
867501
CA DPR Chem Code: 486
Molecular Weight: 338.4
Molecular Structure:
Use Type: Insecticide , Synergist
Chem Class: Unclassified
View Related Chemicals
 
Additional Resources About This Chemical Class and Use Type
Historical Use of this Chemical
Top five crops and sites for this pesticide in California
Structural Pest Control   Public Health Pest Control   Strawberries   Outdoor Container Nursery   Outdoor Flower Nursery  
View All Crops and Sites
 
Other Names for this Chemical
About Chemical Synonyms
(US EPA PC Code ) , (US EPA PC Code ) , (Butylcarbityl)(6-propylpiperonyl) ether 80% and related compounds 20% , 067501 (US EPA PC Code Text ) , 070 (PDP Code) , 1,3-Benzodioxole, 5-((2-(2-butoxyethoxy)ethoxy)methyl)-6-propyl- , 486 (CA DPR Chem Code) ) , 5-((2-(2-Butoxyethoxy)ethoxy)methyl)-6-propyl-1,3-benzodioxole , 5-[[2-(2-Butoxyethoxy)ethoxy]methyl]-6-propyl-1,3-benzodioxole , 51-03-6 (CAS number) , 51036 , 51036 (CAS number without hyphens) , 6-Propylpiperonyl butyl diethyleneglycol ether , 867501 (US EPA PC Code Text ) , alpha-(2-(2-Butoxyethoxy)ethoxy)-4,5-(methylenedioxy)-2-propyltoluene , Butacide , Butyl carbitol 6-propylpiperonyl ether , But?xido de piperonilo , ENT 14250 , ENT-14250 , PBO , Piperony butoxide , piperonyl , Piperonyl butoxide , PIPERONYL BUTOXIDE (CA DPR Chem Code Text ) , piperonyl butoxyde , piperonylbutoksid , Piperonylbutoxid (Synergist) , Piperonylbutoxide , Piperonylbutoxyd , Pybuthrin
 
Products Containing This Chemical
Current and historic U.S. registered products
View U.S. Products All Products Currently Registered Products
 

Signs and Symptoms of Piperonyl butoxide Poisoning

NOTE! There may be other diseases and chemicals that have similar symptoms.

If you have a poisoning emergency in the United States call 1-800-222-1222.
If the victim has collapsed or is unconscious, call 911.

Symptoms of Piperonyl butoxide Exposure from the International Chemical Safety Cards (ICSC)

Report a Poisoning

View full ICSC Cards: English   Español   Française   Chinese   Dutch   Finnish   German   Hungarian   Japanese   Swahili   Thai   Urdu  
NOTE! PREVENT GENERATION OF MISTS!

Route of Exposure

Symptoms

First Aid

Inhalation Fresh air rest.
Skin Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes First rinse with plenty of water for several minutes (remove contact lenses if easily possible) then take to a doctor.
Ingestion Diarrhoea. Vomiting. Rinse mouth. Give plenty of water to drink. Rest. Refer for medical attention.
Notes for ICSC Information
 

Toxicity Information for Piperonyl butoxide

  Note: Information for many chemicals is incomplete and may not be fully representative of effects on humans. Why?

Summary Toxicity Information

PAN Bad Actor
Chemical
1
Acute
Toxicity
2
Carcinogen Cholinesterase
Inhibitor
Ground
Water Contaminant
Developmental or
Reproductive Toxin
Endocrine
Disruptor
Not Listed Moderate Possible No Potential
Suspected
 
Indicates high toxicity in the given toxicological category. Indicates no available weight-of-the-evidence summary assessment. For additional information on toxicity from scientific journals or registration documents, see the "Additional Resources for Toxicity " section of the chemical detail page.
1. PAN Bad Actors are chemicals that are one or more of the following: highly acutely toxic, cholinesterase inhibitor, known/probable carcinogen, known groundwater pollutant or known reproductive or developmental toxicant. NOTE! Because there are no authoritative lists of Endocrine Disrupting (ED) chemicals, EDs are not yet considered PAN Bad Actor chemicals.
2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.

Detailed Toxicity Information

Acute Toxicity 2
Piperonyl butoxide
WHO Acute Hazard
TRI Acute Hazard
Material Safety Data Sheets
Acute rating from U.S. EPA product label
U.S. NTP Acute Toxicity Studies
      View Studies
Cholinesterase Inhibitor
U, Unlikely to be Hazardous
Not Listed
Not Available
Slightly Toxic
Not Acutely Toxic to Moderately Toxic

No
2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.
 
Cancer Information
Piperonyl butoxide
IARC Carcinogens
U.S. NTP Carcinogens
California Prop 65 Known Carcinogens
U.S. EPA Carcinogens
TRI Carcinogen
3, Unclassifiable
Not Listed
Not Listed
C, Possible
Not Listed
 
Endocrine Disruption
Piperonyl butoxide
Illinois EPA list
Keith list
Colborn list
Benbrook list
Danish Inert list
EU list
Not listed
Not listed
Not listed
Not listed
Not listed
Yes
 
Reproductive and Developmental Toxicity
Piperonyl butoxide
CA Prop 65 Developmental Toxin
U.S. TRI Developmental Toxin
CA Prop 65 Female Reproductive Toxin
CA Prop 65 Male Reproductive Toxin
U.S. TRI Reproductive Toxin
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
 
Chemicals of Special Concern
Piperonyl butoxide
PAN Bad Actors
PAN Dirty Dozen list
Not Listed
Not Listed
 

Water Pollution Potential and Criteria for Piperonyl butoxide

Water Pollution Potential

PAN Ground Water Contaminant Rating Potential
 
Physical Property Data Related to Water Contamination Potential
Water Solubility (Avg, mg/L)
Adsorption Coefficient (Koc)
Hydrolysis Half-life (Avg, Days)
Aerobic Soil Half-life (Avg, Days)
Anaerobic Soil Half-life (Avg, Days)
14.0
1,810
251.0
79.0
927.0
 
 

Sorry, no water quality standards or criteria have been established for this chemical by the U.S. or Canadian governments; however, there may be criteria established for related chemicals.

 

Regulatory Information for Piperonyl butoxide

International Regulatory Status

 
UNEP Persistent Organic Pollutant (POP)
UNEP Prior Informed Consent Chemical (PIC)
WHO Obsolete Pesticide
Not Listed
Not Listed
Not Listed
 

U.S. and California Regulatory Status

U.S. EPA Registered
U.S. EPA Hazardous Air Pollutant
U.S. EPA Minimum Risk Pesticide (25b list)

CA Registered
CA Groundwater Contaminant
CA Toxic Air Contaminant
Yes
Not Listed
No

Yes
Potential
Not Listed
 

Maximum Tolerance and Residue Levels

Codex Alimentarius
   (UN FAO Maximum Residue Limits)
U.S. Maximum Tolerance Levels
European Union Maximum Residue Levels
Go to web site

Go to web site

Go to web site
 

Ecotoxicity for Piperonyl butoxide

Note! Information for many chemicals is incomplete and may not be fully representative of effects on the environment. Why? Click on underlined terms for definitions and additional information.

Aquatic Ecotoxicity

All Toxic Effects for Organism Group
Organism Group Effects Noted
Amphibians Enzyme(s), Morphology, Mortality
Annelida Mortality
Crustaceans Accumulation, Mortality
Fish Biochemistry, Development, Enzyme(s), Genetics, Mortality
Insects Enzyme(s), Intoxication, Mortality
Molluscs Intoxication, Mortality, Physiology
Phytoplankton Cell(s), Population
Zooplankton Enzyme(s), Growth, Intoxication, Mortality, Population, Reproduction
View All Aquatic Ecotoxicity Studies and References
 
Summary of Acute Toxicity for Organism Group
Organism Group Average Acute Toxicity Acute Toxicity Range
Amphibians Slightly Toxic Slight to High Toxicity
Annelida Moderately Toxic Moderate Toxicity
Crustaceans Moderately Toxic Slight to Very High Toxicity
Fish Moderately Toxic Moderate Toxicity
Insects Moderately Toxic Moderate Toxicity
Molluscs Not Acutely Toxic Not Acutely Toxic
Zooplankton Moderately Toxic Moderate to High Toxicity
View All Acute Summaries
 

Terrestrial Ecotoxicity

Summary of Acute Toxicity for Organism Group
Organism Group Average Acute Toxicity Acute Toxicity Range
HoneybeesModerately ToxicModerately Toxic
Note: Population-level effects on honeybees may occur even if a pesticide has low acute toxicity. For example, certain pesticides interfere with honeybee reproduction, ability to navigate, or temperature regulation, any of which can have an effect on long-term survival of honeybee colonies. The neonicotinoids, pyrethroids and keto-enol pesticides are some types of pesticides causing one or more of these effects.
Honeybee Chronic Toxicity

Sorry, no honeybee chronic toxicity data available for this chemical. Try related chemicals.

Related Chemicals for Piperonyl butoxide

CAS Number Relation Reason Chemical Name Chem Detail Symptoms California Use Chem Use Type U.S. EPA Reg PAN Bad Actor
51-03-6 Parent P Piperonyl butoxide View View View Insecticide, Synergist Yes Not Listed
Related 8 Piperonyl butoxide, technical, other related View View View Synergist No Not Listed
 
Working with the Information on this Page

Click on underlined terms for definitions or go to the Pesticide Tutorial overview page.

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* Data marked with an asterisk indicates that this chemical is not explicitly listed on the corresponding list. Instead, it belongs to a group of chemicals that IS designated on the list. For example, if an agency assigns a classification of reproductive toxicant to "mercury compounds", that classification is applied to all mercury compounds in the PAN Pesticide database, which are then marked with an asterisk.

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