PAN Pesticides Database - Chemicals

Trichlorfon - Identification, toxicity, use, water pollution potential, ecological toxicity and regulatory information

Note: See Working with the Information on this Page section below for important notes about this data.

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Identifying information, including synonyms, ID numbers, use type, chemical classification, a link to a list of all products containing this chemical and a list of the top crops this pesticide is used on in California.
Signs and symptoms of poisoning, first aid, and links to treatment information for this chemical.
Link to information on toxicity to humans, including carcinogenicity, reproductive and developmental toxicity, neurotoxicity, and acute toxicity.
Links to world-wide registration status as well as regulatory information for the U.S. and California.
Water quality standards and physical properties affecting water contamination potential.
Toxicity to aquatic organisms.
List of chemicals in the same family, including breakdown products, salts, esters, isomers, and other derivatives.

Chemical Identification and Use for Trichlorfon

Basic Identification Information About This Chemical
Chemical Name: Trichlorfon
CAS Number: 52-68-6
U.S. EPA PC Code: 057901
CA DPR Chem Code: 88
Molecular Weight: 257.44
Use Type: Insecticide
Chem Class: Organophosphorus
View Related Chemicals
Additional Resources About This Chemical Class and Use Type
Historical Use of this Chemical
Top five crops and sites for this pesticide in California
Structural Pest Control   Landscape  
View All Crops and Sites
Other Names for this Chemical
About Chemical Synonyms
(US EPA PC Code ) , (1-Hydroxy-2,2,2-trichloroethyl)phosphonic acid, dimethyl ester , (2,2,2-Trichloro-1-hydroxyethyl) dimethylphosphonate , (2,2,2-Trichloro-1-hydroxyethyl)phosphonic acid, dimethyl ester , 057901 (US EPA PC Code Text ) , 52-68-6 (CAS number) , 52686 , 52686 (CAS number without hyphens) , 88 (CA DPR Chem Code) ) , Agroforotox , Anthon , Bay 1359 , Bay 15922 , Bayer 2349 , Bayer L 1359 , Bovinox , Briten , Cekufon , Chlorfos , Chloroftalm , Chloroxyphos , Ciclosom , Danex , DEP (pesticide) , DETF , Dimethoxy (2,2,2-trichloro-1-hydroxyethyl)phosphine oxide , Dimethoxy-2,2,2-trichloro-1-hydroxyethylphosphine oxide , Dimethyl (1-hydroxy-2,2,2-trichloroethyl)phosphonate , Dimethyl (2,2,2-trichloro-1-hydroxyethyl)phosphonate , Dimethyl (trichlorohydroxyethyl)phosphonate , Dipterex , Dipterex 50 , Diptevur , Ditrifon , Dylox , ENT 19763 , Equino-Aid , Flibol E , Fliegenteller , Forotox , Foschlor , Foschlorine , Hypodermacid , Loisol , Masoten , Mazoten , Methyl chlorophos , Metrifonate , Metrifonatum , Metriphonate , NCI-C54831 , Neguvon , O,O-Dimethyl (1-hydroxy-2,2,2-trichloroethyl)phosphonate , O,O-Dimethyl (2,2,2-trichlorohydroxyethyl)phosphonate , OMS 800 , OMS-0800 , P-(2,2,2-Trichloro-1-hydroxyethyl)phosphonic acid dimethyl ester , Phoschlor , Phosphonic acid, (1-hydroxy-2,2,2-trichloroethyl)-, dimethyl ester , Phosphonic acid, (2,2,2-trichloro-1-hydroxyethyl)-, dimethyl ester , Polfoschlor , Proxol , Ricifon , Ritsifon , Soldep , Trichloorfon , Trichlorfon , TRICHLORFON (CA DPR Chem Code Text ) , Trichlorfon (Chlorophos) , Trichlorfon (Trichlorphon) , Trichlorfon [Phosphonic acid, (2,2,2-trichloro-1-hydroxyethyl)-,dimethyl ester] , Trichlorofon , Trichlorophon , Trichlorphon , Triclorfom , Triclorfon , Triclorf?o
Products Containing This Chemical
Current and historic U.S. registered products
View U.S. Products All Products Currently Registered Products

Signs and Symptoms of Trichlorfon Poisoning

NOTE! There may be other diseases and chemicals that have similar symptoms.

If you have a poisoning emergency in the United States call 1-800-222-1222.
If the victim has collapsed or is unconscious, call 911.

Trichlorfon is a Organophosphorus compound.

Report a Poisoning

Symptoms of Poisoning with Organophosphorus Compounds
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- Excessive salivation, sweating, rhinorrhea and tearing.
- Muscle twitching, weakness, tremor, incoordination.
- Headache, dizziness, nausea, vomiting, abdominal cramps, diarrhea.
- Respiratory depression, tightness in chest, wheezing, productive cough, fluid in lungs.
- Pin-point pupils, sometimes with blurred or dark vision.
- Severe cases: seizures, incontinence, respiratory depression, loss of consciousness.
- Cholinesterase inhibition.

Source for Group Symptoms: Recognition and Management of Pesticide Poisoning, 5th edition, U.S. EPA, Chapter 4.

Treatment for Organophosphorus Poisoning

See: Recognition and Management of Pesticide Poisoning, 5th edition, U.S. EPA, Chapter 4, page 40.

Symptoms of Trichlorfon Exposure from the International Chemical Safety Cards (ICSC)

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View full ICSC Cards: English   Español   Française   Chinese   Dutch   Finnish   German   Hungarian   Japanese   Swahili   Thai   Urdu  

Route of Exposure


First Aid

Inhalation Convulsions. Dizziness. Sweating. Laboured breathing. Nausea. Unconsciousness. Vomiting. Pupillary constriction muscle cramp excessive salivation. Symptoms may be delayed (see Notes). Fresh air rest. Refer for medical attention.
Skin MAY BE ABSORBED! (See Inhalation). Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.
Eyes Redness. Pain. Pupillary constriction. Blurred vision. First rinse with plenty of water for several minutes (remove contact lenses if easily possible) then take to a doctor.
Ingestion Abdominal cramps. Diarrhoea. Laboured breathing. Nausea. Unconsciousness. Vomiting. Weakness. Pupillary constriction muscle cramps excessive salivation. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Rest. Refer for medical attention.
Notes for ICSC Information
Depending on the degree of exposure periodic medical examination is indicated. The symptoms of acute intoxication do not become manifest until some hours have passed. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. The recommendations on this card apply to the pure form. Commercial formulations are often mixtures including impurities solvent or other agents which modify toxic and physicochemical properties. Acrol DEP DANEX DIMETOX are trade names.

Toxicity Information for Trichlorfon

  Note: Information for many chemicals is incomplete and may not be fully representative of effects on humans. Why?

Summary Toxicity Information

PAN Bad Actor
Carcinogen Cholinesterase
Water Contaminant
Developmental or
Reproductive Toxin
Indicates high toxicity in the given toxicological category. Indicates no available weight-of-the-evidence summary assessment. For additional information on toxicity from scientific journals or registration documents, see the "Additional Resources for Toxicity " section of the chemical detail page.
1. PAN Bad Actors are chemicals that are one or more of the following: highly acutely toxic, cholinesterase inhibitor, known/probable carcinogen, known groundwater pollutant or known reproductive or developmental toxicant. NOTE! Because there are no authoritative lists of Endocrine Disrupting (ED) chemicals, EDs are not yet considered PAN Bad Actor chemicals.
2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.

Detailed Toxicity Information

Acute Toxicity 2
WHO Acute Hazard
TRI Acute Hazard
Material Safety Data Sheets
Acute rating from U.S. EPA product label
U.S. NTP Acute Toxicity Studies
      View Studies
Cholinesterase Inhibitor
II, Moderately Hazardous
Not Listed
Not Available
Moderately Toxic
Slightly to Moderately Toxic

2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.
Cancer Information
IARC Carcinogens
U.S. NTP Carcinogens
California Prop 65 Known Carcinogens
U.S. EPA Carcinogens
TRI Carcinogen
3, Unclassifiable
Not Listed
Not Listed
Likely (high doses), Not likely (low doses)
Not Listed
Endocrine Disruption
Illinois EPA list
Keith list
Colborn list
Benbrook list
Danish Inert list
EU list
Not listed
Not listed
Not listed
Not listed
Not listed
Reproductive and Developmental Toxicity
CA Prop 65 Developmental Toxin
U.S. TRI Developmental Toxin
CA Prop 65 Female Reproductive Toxin
CA Prop 65 Male Reproductive Toxin
U.S. TRI Reproductive Toxin
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Chemicals of Special Concern
PAN Bad Actors
PAN Dirty Dozen list
Not Listed

Water Pollution Potential and Criteria for Trichlorfon

Water Pollution Potential

PAN Ground Water Contaminant Rating Insufficient Data
Physical Property Data Related to Water Contamination Potential
Water Solubility (Avg, mg/L)
Adsorption Coefficient (Koc)
Hydrolysis Half-life (Avg, Days)
Aerobic Soil Half-life (Avg, Days)
Anaerobic Soil Half-life (Avg, Days)

Water Standards and Criteria

WHO Water Quality Criteria
Description Unlikely to occur in drinking-water
Notes Notes: e

Regulatory Information for Trichlorfon

International Regulatory Status

UNEP Persistent Organic Pollutant (POP)
UNEP Prior Informed Consent Chemical (PIC)
WHO Obsolete Pesticide
Not Listed
Not Listed
Not Listed

U.S. and California Regulatory Status

U.S. EPA Registered
U.S. EPA Hazardous Air Pollutant
U.S. EPA Minimum Risk Pesticide (25b list)

CA Registered
CA Groundwater Contaminant
CA Toxic Air Contaminant
Not Listed

Not Listed
Not Listed

Maximum Tolerance and Residue Levels

Codex Alimentarius
   (UN FAO Maximum Residue Limits)
U.S. Maximum Tolerance Levels
European Union Maximum Residue Levels
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Ecotoxicity for Trichlorfon

Note! Information for many chemicals is incomplete and may not be fully representative of effects on the environment. Why? Click on underlined terms for definitions and additional information.

Aquatic Ecotoxicity

All Toxic Effects for Organism Group
Organism Group Effects Noted
Amphibians Biochemistry, Cell(s), Growth, Mortality
Annelida Behavior, Histology, Mortality, Population
Crustaceans Behavior, Biochemistry, Cell(s), Enzyme(s), Genetics, Mortality, Physiology, Population
Fish Accumulation, Behavior, Biochemistry, Cell(s), Development, Enzyme(s), Genetics, Growth, Histology, Hormone(s), Intoxication, Morphology, Mortality, No Effect Coded, Physiology, Population, Reproduction
Insects Behavior, Histology, Intoxication, Mortality, Population
Molluscs Accumulation, Behavior, Biochemistry, Growth, Histology, Mortality, Physiology, Population
NematodesandFlatworms Histology, Intoxication, Mortality, Population
Phytoplankton Biochemistry, Genetics, Growth, Mortality, Physiology, Population
Zooplankton Accumulation, Behavior, Intoxication, Mortality, Population, Reproduction
~ Un-Assigned Mortality, Physiology, Population
View All Aquatic Ecotoxicity Studies and References
Summary of Acute Toxicity for Organism Group
Organism Group Average Acute Toxicity Acute Toxicity Range
Amphibians Slightly Toxic Slight Toxicity
Annelida Slightly Toxic Slight to High Toxicity
Crustaceans Highly Toxic Moderate to Very High Toxicity
Fish Slightly Toxic Not Acutely Toxic to High Toxicity
Insects Moderately Toxic Slight to Very High Toxicity
Molluscs Moderately Toxic Slight to High Toxicity
Zooplankton Slightly Toxic Slight to Very High Toxicity
~ Un-Assigned Highly Toxic Moderate to Very High Toxicity
View All Acute Summaries

Terrestrial Ecotoxicity

Summary of Acute Toxicity for Organism Group
Organism Group Average Acute Toxicity Acute Toxicity Range
HoneybeesSlightly ToxicSlightly Toxic
Note: Population-level effects on honeybees may occur even if a pesticide has low acute toxicity. For example, certain pesticides interfere with honeybee reproduction, ability to navigate, or temperature regulation, any of which can have an effect on long-term survival of honeybee colonies. The neonicotinoids, pyrethroids and keto-enol pesticides are some types of pesticides causing one or more of these effects.
Honeybee Chronic Toxicity

Sorry, no honeybee chronic toxicity data available for this chemical. Try related chemicals.

Related Chemicals for Trichlorfon

CAS Number Relation Reason Chemical Name Chem Detail Symptoms California Use Chem Use Type U.S. EPA Reg PAN Bad Actor
52-68-6 Parent P Trichlorfon View View View Insecticide Yes Yes
Working with the Information on this Page

Click on underlined terms for definitions or go to the Pesticide Tutorial overview page.

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* Data marked with an asterisk indicates that this chemical is not explicitly listed on the corresponding list. Instead, it belongs to a group of chemicals that IS designated on the list. For example, if an agency assigns a classification of reproductive toxicant to "mercury compounds", that classification is applied to all mercury compounds in the PAN Pesticide database, which are then marked with an asterisk.

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