PAN Pesticides Database - Chemicals

4-CPA - Identification, toxicity, use, water pollution potential, ecological toxicity and regulatory information

Note: See Working with the Information on this Page section below for important notes about this data.

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Identifying information, including synonyms, ID numbers, use type, chemical classification, a link to a list of all products containing this chemical and a list of the top crops this pesticide is used on in California.
Signs and symptoms of poisoning, first aid, and links to treatment information for this chemical.
Link to information on toxicity to humans, including carcinogenicity, reproductive and developmental toxicity, neurotoxicity, and acute toxicity.
Links to world-wide registration status as well as regulatory information for the U.S. and California.
Water quality standards and physical properties affecting water contamination potential.
Toxicity to aquatic organisms.
List of chemicals in the same family, including breakdown products, salts, esters, isomers, and other derivatives.
 

Chemical Identification and Use for 4-CPA

Basic Identification Information About This Chemical
Chemical Name: 4-CPA
CAS Number: 122-88-3
U.S. EPA PC Code: 019401
CA DPR Chem Code: 643
Molecular Weight: 186.59
Use Type: Plant Growth Regulator
Chem Class: Chlorophenoxy acid or ester
View Related Chemicals
 
Additional Resources About This Chemical Class and Use Type

See the Global Pesticide Resources page for many additional links.

 
Other Names for this Chemical
About Chemical Synonyms
00643 (CA DPR Chem Code Text) , 00643 (CA DPR Chem Code) , 019401 (US EPA PC Code Text) , 122-88-3 (CAS number) , 122883 , 122883 (CAS number without hyphens) , 19401 (US EPA PC Code) , 4-Chlorophenoxyacetic acid , 4-CPA , 4CPA , 643 (CA DPR Chem Code) , 643 (CA DPR Chem Code) , Acetic acid, (4-chlorophenoxy)- , Acetic acid, (p-chlorophenoxy)- , acide chloro-4-phenoxyacetique , Marks 4-CPA , p-Chlorophenoxyacetic acid , PCPA , Phenoxyacetic acid, 4-chloro- , Sure-Set , Tomato Fix Concentrate , Tomato Hold , Tomatotone
 
Products Containing This Chemical
Current and historic U.S. registered products
View U.S. Products All Products Currently Registered Products
 

Signs and Symptoms of 4-CPA Poisoning

NOTE! There may be other diseases and chemicals that have similar symptoms.

If you have a poisoning emergency in the United States call 1-800-222-1222.
If the victim has collapsed or is unconscious, call 911.

4-CPA is a Chlorophenoxy compound.

Report a Poisoning

Symptoms of Poisoning with Chlorophenoxy Compounds
Find Products Containing this Chemical

- Irritation of skin, eyes and respiratory tract.
- Inhalation may cause burning sensation in nasopharynx and chest, coughing, and/or dizziness.
- Headache, vomiting, diarrhea.
- Confusion, bizarre or aggressive behavior.
- Kidney failure, increased heart rate.
- Metabolic acidosis resulting in peculiar odor on breath.

Source for Group Symptoms: Recognition and Management of Pesticide Poisoning, 5th edition, U.S. EPA, Chapter 9.

Treatment for Chlorophenoxy Poisoning

See: Recognition and Management of Pesticide Poisoning, 5th edition, U.S. EPA, Chapter 9, page 96.

 
 

Toxicity Information for 4-CPA

  Note: Information for many chemicals is incomplete and may not be fully representative of effects on humans. Why?

Summary Toxicity Information

PAN Bad Actor
Chemical
1
Acute
Toxicity
2
Carcinogen Cholinesterase
Inhibitor
Ground
Water Contaminant
Developmental or
Reproductive Toxin
Endocrine
Disruptor
Not Listed Slight Possible No
 
Indicates high toxicity in the given toxicological category. Indicates no available weight-of-the-evidence summary assessment. For additional information on toxicity from scientific journals or registration documents, see the "Additional Resources for Toxicity " section of the chemical detail page.
1. PAN Bad Actors are chemicals that are one or more of the following: highly acutely toxic, cholinesterase inhibitor, known/probable carcinogen, known groundwater pollutant or known reproductive or developmental toxicant. NOTE! Because there are no authoritative lists of Endocrine Disrupting (ED) chemicals, EDs are not yet considered PAN Bad Actor chemicals.
2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.

Additional Resources about the Toxicity of this Chemical

See the Global Pesticide Resources page for many additional links.

Detailed Toxicity Information

Acute Toxicity 2
4-CPA
WHO Acute Hazard
TRI Acute Hazard
Material Safety Data Sheets
Acute rating from U.S. EPA product label
U.S. NTP Acute Toxicity Studies
      View Studies
Cholinesterase Inhibitor
III, Slightly Hazardous
Not Listed
Not Available

No NTP Studies

No
2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.
 
Cancer Information
4-CPA
IARC Carcinogens
U.S. NTP Carcinogens
California Prop 65 Known Carcinogens
U.S. EPA Carcinogens
TRI Carcinogen
2B, Possible
Not Listed
Not Listed
Not Listed
Not Listed
 
Endocrine Disruption
4-CPA
Illinois EPA list
Keith list
Colborn list
Benbrook list
Danish Inert list
EU list
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
 
Reproductive and Developmental Toxicity
4-CPA
CA Prop 65 Developmental Toxin
U.S. TRI Developmental Toxin
CA Prop 65 Female Reproductive Toxin
CA Prop 65 Male Reproductive Toxin
U.S. TRI Reproductive Toxin
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
 
Chemicals of Special Concern
4-CPA
PAN Bad Actors
PAN Dirty Dozen list
Not Listed
Not Listed
 

Water Pollution Potential and Criteria for 4-CPA

Water Pollution Potential

PAN Ground Water Contaminant Rating Insufficient Data
 

Sorry, no water quality standards or criteria have been established for this chemical by the U.S. or Canadian governments; however, there may be criteria established for related chemicals.

 

Regulatory Information for 4-CPA

International Regulatory Status

Registration in Selected Countries Registration in Selected Countries:
4-CPA

 
UNEP Persistent Organic Pollutant (POP)
UNEP Prior Informed Consent Chemical (PIC)
WHO Obsolete Pesticide
Not Listed
Not Listed
Not Listed
 

U.S. and California Regulatory Status

U.S. EPA Registered
U.S. EPA Hazardous Air Pollutant
U.S. EPA Minimum Risk Pesticide (25b list)

CA Registered
CA Groundwater Contaminant
CA Toxic Air Contaminant
Yes
Not Listed
No

No
Not Listed
Not Listed
 

Maximum Tolerance and Residue Levels

Codex Alimentarius
   (UN FAO Maximum Residue Limits)
U.S. Maximum Tolerance Levels
European Union Maximum Residue Levels
Go to web site

Go to web site

Go to web site
 

Ecotoxicity for 4-CPA

Note! Information for many chemicals is incomplete and may not be fully representative of effects on the environment. Why? Click on underlined terms for definitions and additional information.

Aquatic Ecotoxicity

All Toxic Effects for Organism Group
Organism Group Effects Noted
Fish Mortality, No Effect Coded
View All Aquatic Ecotoxicity Studies and References
 
Summary of Acute Toxicity for Organism Group
Organism Group Average Acute Toxicity Acute Toxicity Range
Fish Not Acutely Toxic Not Acutely Toxic
View All Acute Summaries
 

Terrestrial Ecotoxicity

Summary of Acute Toxicity for Organism Group

Sorry, no honeybee acute toxicity data available for this chemical. Try related chemicals.

Note: Population-level effects on honeybees may occur even if a pesticide has low acute toxicity. For example, certain pesticides interfere with honeybee reproduction, ability to navigate, or temperature regulation, any of which can have an effect on long-term survival of honeybee colonies. The neonicotinoids, pyrethroids and keto-enol pesticides are some types of pesticides causing one or more of these effects.
Honeybee Chronic Toxicity

Sorry, no honeybee chronic toxicity data available for this chemical. Try related chemicals.

Related Chemicals for 4-CPA

CAS Number Relation Reason Chemical Name Chem Detail Registration Symptoms California Use Chem Use Type U.S. EPA Reg PAN Bad Actor
122-88-3 Parent P 4-CPA View View View View Plant Growth Regulator Yes Not Listed
13730-98-8 Related 1 4-chlorophenoxyacetic acid, sodium salt View View View View Plant Growth Regulator No Not Listed
53404-23-2 Related 1 4-CPA, diethanolamine salt View View View View Plant Growth Regulator No Not Listed
 
Working with the Information on this Page

Click on underlined terms for definitions or go to the Pesticide Tutorial overview page.

Any underlined term with a book icon has additional information.

* Data marked with an asterisk indicates that this chemical is not explicitly listed on the corresponding list. Instead, it belongs to a group of chemicals that IS designated on the list. For example, if an agency assigns a classification of reproductive toxicant to "mercury compounds", that classification is applied to all mercury compounds in the PAN Pesticide database, which are then marked with an asterisk.

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