PAN Pesticides Database - Chemicals

Metolachlor - Identification, toxicity, use, water pollution potential, ecological toxicity and regulatory information

Note: See Working with the Information on this Page section below for important notes about this data.

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Identifying information, including synonyms, ID numbers, use type, chemical classification, a link to a list of all products containing this chemical and a list of the top crops this pesticide is used on in California.
Signs and symptoms of poisoning, first aid, and links to treatment information for this chemical.
Link to information on toxicity to humans, including carcinogenicity, reproductive and developmental toxicity, neurotoxicity, and acute toxicity.
Links to world-wide registration status as well as regulatory information for the U.S. and California.
Water quality standards and physical properties affecting water contamination potential.
Toxicity to aquatic organisms.
List of chemicals in the same family, including breakdown products, salts, esters, isomers, and other derivatives.
 

Chemical Identification and Use for Metolachlor

Basic Identification Information About This Chemical
Chemical Name: Metolachlor
CAS Number: 51218-45-2
U.S. EPA PC Code: 108801
288700 (Old US EPA PC Code.)
CA DPR Chem Code: 1996
Molecular Weight: 283.81
Use Type: Herbicide
Chem Class: Chloroacetanilide
View Related Chemicals
 
Additional Resources About This Chemical Class and Use Type
Historical Use of this Chemical
Top five crops and sites for this pesticide in California
Tomatoes for Processing   Corn for Forage   Dried Beans   Sorghum   Corn  
View All Crops and Sites
 
Other Names for this Chemical
About Chemical Synonyms
(US EPA PC Code ) , (US EPA PC Code ) , 108801 (US EPA PC Code Text ) , 1996 (CA DPR Chem Code) ) , 2-Chloro-6'-ethyl-N-(2-methoxy-1-methylethyl)-o-acetotoluidide , 2-chloro-6'-ethyl-N-(2-methoxy-1-methylethyl)acet-o-toluidide , 2-Chloro-N-(2-ethyl-6-methylphenyl)-N-(2-methoxy-1-methylethyl)acetamide , 2-Chloro-N-(2-ethyl-6-methylphenyl)-N-(2-methoxy-1-methylphenyl)acetamide , 283 (PDP Code) , 288700 (Old US EPA PC Code) , 288700 (US EPA PC Code Text ) , 51218-45-2 (CAS number) , 51218452 , 51218452 (CAS number without hyphens) , Acetamide, 2-chloro-N-(2-ethyl-6-methylphenyl)-N-(2-methoxy-1-methylethyl)- , Acetamide, 2-chloro-N-(6-ethyl-o-tolyl)-N-(2-methoxy-1-methylethyl)- , Bicep , CGA 24705 , CGA-24705 , Codal , Cotoran Multi , Dual , Methanesulfonamide, 1,1,1-trifluoro-N-(2-methyl-4-(phenylsulfonyl)phenyl)- , Metholachlore , Metolachlor , Metolachlor (ANSI) , METOLACHLOR (CA DPR Chem Code Text ) , metolachlore , Metolacloro , Metolakl?r , Metolochlor , Milocep, component of (with 080808) , Milocep, component of (with 080808) , N-(2'-Methoxy-1'-methylethyl)-2'-ethyl-6'-methyl-2-chloroacetanilide , o-Acetotoluidide, 2-chloro-6'-ethyl-N-(2-methoxy-1-methylethyl)- , Ontrack 8E , Pennant , Primagram , Primextra , S-Metolachlor and R-enantiomer , Use code no. 108801
 
Products Containing This Chemical
Current and historic U.S. registered products
View U.S. Products All Products Currently Registered Products
 

Signs and Symptoms of Metolachlor Poisoning

NOTE! There may be other diseases and chemicals that have similar symptoms.

If you have a poisoning emergency in the United States call 1-800-222-1222.
If the victim has collapsed or is unconscious, call 911.

Symptoms of Metolachlor Exposure from the International Chemical Safety Cards (ICSC)

Report a Poisoning

View full ICSC Cards: English   Español   Française   Chinese   Dutch   Finnish   German   Hungarian   Japanese   Swahili   Thai   Urdu  
NOTE!
General First Aid: IN ALL CASES CONSULT A DOCTOR!

Route of Exposure

Symptoms

First Aid

Inhalation Headache. Nausea. Fresh air rest.
Skin Rinse and then wash skin with water and soap.
Eyes First rinse with plenty of water for several minutes (remove contact lenses if easily possible) then take to a doctor.
Ingestion Abdominal cramps. Give plenty of water to drink. Refer for medical attention.
Notes for ICSC Information
If the substance is formulated with solvent(s) also consult the card(s) (ICSC) of the solvent(s). Carrier solvents used in commercial formulations may change physical and toxicological properties.
Symptoms of Metolachlor Exposure from Other Sources

- Irritation of skin and eyes.

Source for Symptoms: Recognition and Management of Pesticide Poisoning, 5th edition, U.S. EPA, Chapter 13. March 1999. (EPA R&M)

First Aid for Metolachlor Poisoning

No first aid available for this particular chemical. Get medical aid.

Source for First Aid: ()

 
 

Toxicity Information for Metolachlor

  Note: Information for many chemicals is incomplete and may not be fully representative of effects on humans. Why?

Summary Toxicity Information

PAN Bad Actor
Chemical
1
Acute
Toxicity
2
Carcinogen Cholinesterase
Inhibitor
Ground
Water Contaminant
Developmental or
Reproductive Toxin
Endocrine
Disruptor
Slight Possible No
Suspected
 
Indicates high toxicity in the given toxicological category. Indicates no available weight-of-the-evidence summary assessment. For additional information on toxicity from scientific journals or registration documents, see the "Additional Resources for Toxicity " section of the chemical detail page.
1. PAN Bad Actors are chemicals that are one or more of the following: highly acutely toxic, cholinesterase inhibitor, known/probable carcinogen, known groundwater pollutant or known reproductive or developmental toxicant. NOTE! Because there are no authoritative lists of Endocrine Disrupting (ED) chemicals, EDs are not yet considered PAN Bad Actor chemicals.
2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.

Detailed Toxicity Information

Acute Toxicity 2
Metolachlor
WHO Acute Hazard
TRI Acute Hazard
Material Safety Data Sheets
Acute rating from U.S. EPA product label
U.S. NTP Acute Toxicity Studies
      View Studies
Cholinesterase Inhibitor
III, Slightly Hazardous
Not Listed
Not Available
Slightly Toxic
No NTP Studies

No
2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.
 
Cancer Information
Metolachlor
IARC Carcinogens
U.S. NTP Carcinogens
California Prop 65 Known Carcinogens
U.S. EPA Carcinogens
TRI Carcinogen
Not Listed
Not Listed
Not Listed
C, Possible
Not Listed
 
Endocrine Disruption
Metolachlor
Illinois EPA list
Keith list
Colborn list
Benbrook list
Danish Inert list
EU list
Not Listed
Yes
Not Listed
Not Listed
Not listed
Not listed
 
Reproductive and Developmental Toxicity
Metolachlor
CA Prop 65 Developmental Toxin
U.S. TRI Developmental Toxin
CA Prop 65 Female Reproductive Toxin
CA Prop 65 Male Reproductive Toxin
U.S. TRI Reproductive Toxin
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
 
Chemicals of Special Concern
Metolachlor
PAN Bad Actors
PAN Dirty Dozen list
Yes
Not Listed
 

Water Pollution Potential and Criteria for Metolachlor

Water Pollution Potential

PAN Ground Water Contaminant Rating Known
 
Physical Property Data Related to Water Contamination Potential
Water Solubility (Avg, mg/L)
Adsorption Coefficient (Koc)
Hydrolysis Half-life (Avg, Days)
Aerobic Soil Half-life (Avg, Days)
Anaerobic Soil Half-life (Avg, Days)
493.0
190.0
200.0
26.0
61.0
 
 

Water Standards and Criteria

U.S. National Drinking Water Standards and Health Criteria
g/L unless noted  
Maximum Contaminant Level (MCL) 0  
Maximum Contaminant Level Goal (MCLG)  
One Day Exposure Health Advisory Level 2,000  
Ten Day Exposure Health Advisory Level 2,000  
Lifetime Exposure Health Advisory Level 700.0  
Reference Dose 100.0 (g/kg/day)  
U.S. Drinking Water Equivalent Level 3,500  
Concentration with Lifetime Cancer Risk of 1 in 10,000  
Canada Drinking Water Standards and Criteria
g/L unless noted  
Maximum Acceptable Concentration (MAC) 50.0
Interim Maximum Acceptable Concentration (IMAC)
Aesthetic Objectives
WHO Water Quality Criteria
Concentration (μg/l unless otherwise noted) 10.0
Canadian Water Quality Guidelines for the Protection of Aquatic Life
g/L unless noted  
Fresh Water Guidelines 7.8 Notes: c
Salt Water Guidelines
Canadian Water Quality Guidelines for the Protection of Agricultural Water Uses
g/L unless noted  
Irrigation Water Guidelines 28
Livestock Water Guidelines 50
 

Regulatory Information for Metolachlor

International Regulatory Status

 
UNEP Persistent Organic Pollutant (POP)
UNEP Prior Informed Consent Chemical (PIC)
WHO Obsolete Pesticide
Not Listed
Not Listed
Not Listed
 

U.S. and California Regulatory Status

U.S. EPA Registered
U.S. EPA Hazardous Air Pollutant
U.S. EPA Minimum Risk Pesticide (25b list)

CA Registered
CA Groundwater Contaminant
CA Toxic Air Contaminant
Yes
Not Listed
No

Yes
Potential
Not Listed
 

Maximum Tolerance and Residue Levels

Codex Alimentarius
   (UN FAO Maximum Residue Limits)
U.S. Maximum Tolerance Levels
European Union Maximum Residue Levels
Go to web site

Go to web site

Go to web site
 

Ecotoxicity for Metolachlor

Note! Information for many chemicals is incomplete and may not be fully representative of effects on the environment. Why? Click on underlined terms for definitions and additional information.

Aquatic Ecotoxicity

All Toxic Effects for Organism Group
Organism Group Effects Noted
Amphibians Development, Genetics, Growth, Morphology, Mortality
AquaticPlants Biochemistry, Development, Ecosystem Process, Growth, Physiology, Population
Cnidaria Growth, Mortality
Crustaceans Behavior
Fish Accumulation, Mortality
Insects Biochemistry, Enzyme(s), Intoxication, Mortality
Molluscs Intoxication
Phytoplankton Accumulation, Biochemistry, Ecosystem Process, Enzyme(s), Physiology, Population
TerrestrialPlants Development, Growth
Zooplankton Accumulation, Growth, Intoxication, Mortality, Population, Reproduction
~ Un-Assigned Biochemistry, Development, Enzyme(s), Growth, Mortality, Physiology, Population
View All Aquatic Ecotoxicity Studies and References
 
Summary of Acute Toxicity for Organism Group
Organism Group Average Acute Toxicity Acute Toxicity Range
Amphibians Not Acutely Toxic Not Acutely Toxic to Slightly Toxic
Cnidaria Slightly Toxic Slight Toxicity
Fish Moderately Toxic Slight to Moderate Toxicity
Insects Slightly Toxic Slight Toxicity
Zooplankton Slightly Toxic Slight to Moderate Toxicity
View All Acute Summaries
 

Terrestrial Ecotoxicity

Summary of Acute Toxicity for Organism Group
Organism Group Average Acute Toxicity Acute Toxicity Range
HoneybeesNot AcutelyT ToxicNot AcutelyT Toxic
Note: Population-level effects on honeybees may occur even if a pesticide has low acute toxicity. For example, certain pesticides interfere with honeybee reproduction, ability to navigate, or temperature regulation, any of which can have an effect on long-term survival of honeybee colonies. The neonicotinoids, pyrethroids and keto-enol pesticides are some types of pesticides causing one or more of these effects.
Honeybee Chronic Toxicity

Sorry, no honeybee chronic toxicity data available for this chemical. Try related chemicals.

Related Chemicals for Metolachlor

CAS Number Relation Reason Chemical Name Chem Detail Symptoms California Use Chem Use Type U.S. EPA Reg PAN Bad Actor
51218-45-2 Parent P Metolachlor View View View Herbicide Yes Yes
Related 5a 2-Ethyl-6-methylaniline View View View Breakdown product No Not Listed
Related 5a 2-[(2-Ethyl-6-methylphenyl)-amino]-1-propanol View View View Breakdown product No Not Listed
Related 5a Metolachlor ethanesulfonic acid View View View Breakdown product No Not Listed
Related 5a Metolachlor oxanilic acid View View View Breakdown product No Not Listed
Related 6 Metolachlor, (R) View View View Herbicide No Not Listed
87392-12-9, 178961-20-1 Related 6 Metolachlor, (S) View View View Herbicide Yes Yes
Related 13 Milocep (Metolachlor(108801) with Propazine(080808)) View View View Herbicide No Not Listed
 
Working with the Information on this Page

Click on underlined terms for definitions or go to the Pesticide Tutorial overview page.

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* Data marked with an asterisk indicates that this chemical is not explicitly listed on the corresponding list. Instead, it belongs to a group of chemicals that IS designated on the list. For example, if an agency assigns a classification of reproductive toxicant to "mercury compounds", that classification is applied to all mercury compounds in the PAN Pesticide database, which are then marked with an asterisk.

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