Carbofuran - toxicity, ecological toxicity and regulatory information

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Carbofuran - Identification, toxicity, use, water pollution potential, ecological toxicity and regulatory information

Note: See Working with the Information on this Page section below for important notes about this data.
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Chemical ID	Identifying information, including synonyms, ID numbers, use type, chemical classification, a link to a list of all products containing this chemical and a list of the top crops this pesticide is used on in California.
Poisoning Symptoms	Signs and symptoms of poisoning, first aid, and links to treatment information for this chemical.
Toxicity	Link to information on toxicity to humans, including carcinogenicity, reproductive and developmental toxicity, neurotoxicity, and acute toxicity.
Regulatory	Links to world-wide registration status as well as regulatory information for the U.S. and California.
Water	Water quality standards and physical properties affecting water contamination potential.
Ecotoxicity	Toxicity to aquatic organisms.
Related Chems	List of chemicals in the same family, including breakdown products, salts, esters, isomers, and other derivatives.

Chemical Identification and Use for Carbofuran

Basic Identification Information About This Chemical
Chemical Name:	Carbofuran
CAS Number:	1563-66-2
U.S. EPA PC Code:	090601
CA DPR Chem Code:	106
Molecular Weight:	221.26
Molecular Structure:
Use Type:	Insecticide , Nematicide
Chem Class:	N-Methyl Carbamate
View Related Chemicals

Additional Resources About This Chemical Class and Use Type
See the Global Pesticide Resources page for many additional links.

Historical Use of this Chemical Top five crops and sites for this pesticide in California
Wine Grapes Alfalfa for Forage View All Crops and Sites

Other Names for this Chemical About Chemical Synonyms
00106 (CA DPR Chem Code Text) , 00106 (CA DPR Chem Code) , 090601 (US EPA PC Code Text) , 106 (CA DPR Chem Code) , 106 (CA DPR Chem Code) , 1563-66-2 (CAS number) , 1563662 , 1563662 (CAS number without hyphens) , 180 (PDP Code) , 2,2-Dimethyl-2,2-dihydrobenzofuranyl-7 N-methylcarbamate , 2,2-Dimethyl-2,3-dihydro-7-benzofuranyl-N-methylcarbamate , 2,2-Dimethyl-2,3-dihydrobenzofuranyl 7-methylcarbamate , 2,2-Dimethyl-7-coumaranyl N-methylcarbamate , 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamate , 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl N-methylcarbamate , 2,3-Dihydro-2,2-dimethylbenzofuran-7-yl methylcarbamate , 7-Benzofuranol, 2,3-dihydro-2,2-dimethyl-, methylcarbamate , 90601 (US EPA PC Code) , Bay 70143 , Bay 78537 , Carbamic acid, methyl-, 2,2-dimethyl-2,3-dihydro-7-benzofuranyl ester , Carbamic acid, methyl-, 2,2-dimethyl-2,3-dihydrobenzofuran-7-yl ester , Carbamic acid, methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester , Carbefuran , Carbofuran , Carbofuran , Carbofuran (ANSI) , Carbofurano , Carbofur?o , Curaterr , D 1221 , ENT 27164 , FMC 10242 , Furadan , Karbofur?n , NIA 10242 , OMS 864 , Pillarfuran , Yaltox

Products Containing This Chemical Current and historic U.S. registered products
View U.S. Products All Products Currently Registered Products

Signs and Symptoms of Carbofuran Poisoning

	NOTE! There may be other diseases and chemicals that have similar symptoms.
	If you have a poisoning emergency in the United States call 1-800-222-1222. If the victim has collapsed or is unconscious, call 911.

Carbofuran is a high toxicity Carbamate compound.

Report a Poisoning

Symptoms of Poisoning with high toxicity Carbamate Compounds			Find Products Containing this Chemical
High Toxicity Carbamate Pesticides: - Malaise, muscle weakness, dizziness, and sweating. - Headache, salivation, nausea, vomiting, abdominal pain, and diarrhea. - Miosis with blurred vision, incoordination, muscle twitching and slurred speech. - In more severe cases: Central nervous system depression (coma, seizures and hypotonicity), hypertension and cardiorespiratory depression. Also dyspnea, bronchospasms and bronchorrhea with eventual pulmonary edema.
Source for Group Symptoms: Recognition and Management of Pesticide Poisoning, 5th edition, U.S. EPA, Chapter 5.
Treatment for high toxicity Carbamate Poisoning
See: Recognition and Management of Pesticide Poisoning, 5th edition, U.S. EPA, Chapter 5, page 50.

Route of Exposure	Symptoms	First Aid
Symptoms of Carbofuran Exposure from the International Chemical Safety Cards (ICSC)		Report a Poisoning
View full ICSC Cards: English Español Française Chinese Dutch Finnish German Hungarian Japanese Swahili Thai Urdu
NOTE! PREVENT DISPERSION OF DUST! STRICT HYGIENE! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN!		General First Aid: IN ALL CASES CONSULT A DOCTOR!
Inhalation	Dizziness. Sweating. Laboured breathing. Unconsciousness. Vomiting. Pupillary constriction muscle cramp excessive salivation.	Fresh air rest. Refer for medical attention. See Notes.
Skin		Rinse and then wash skin with water and soap.
Eyes		First rinse with plenty of water for several minutes (remove contact lenses if easily possible) then take to a doctor.
Ingestion	Abdominal cramps. Diarrhoea. Headache. Nausea. Vomiting. Weakness. (Further see Inhalation).	Give a slurry of activated charcoal in water to drink. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Rest. Refer for medical attention.
Notes for ICSC Information
Temperature of decomposition unknown in literature. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. Carrier solvents used in commercial formulations may change physical and toxicological properties. Do NOT take working clothes home. Bay 70143 Curaterr FMC 10242 Furadan Niagara 10242 Pillarfuran and Yaltox are trade names. If the substance is present under the form of a formulation containing hydrocarbon solvents vomiting may not be induced.

Toxicity Information for Carbofuran

Note: Information for many chemicals is incomplete and may not be fully representative of effects on humans. Why?

PAN Bad Actor Chemical¹	Carcinogen	Ground Water Contaminant	Endocrine Disruptor
Summary Toxicity Information
	Not Likely	Potential	Suspected

	Indicates high toxicity in the given toxicological category.	Indicates no available weight-of-the-evidence summary assessment. For additional information on toxicity from scientific journals or registration documents, see the "Additional Resources for Toxicity " section of the chemical detail page.
1. PAN Bad Actors are chemicals that are one or more of the following: highly acutely toxic, cholinesterase inhibitor, known/probable carcinogen, known groundwater pollutant or known reproductive or developmental toxicant. NOTE! Because there are no authoritative lists of Endocrine Disrupting (ED) chemicals, EDs are not yet considered PAN Bad Actor chemicals.
2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.

Additional Resources about the Toxicity of this Chemical

See the Global Pesticide Resources page for many additional links.

Detailed Toxicity Information
Acute Toxicity ²	Carbofuran
WHO Acute Hazard TRI Acute Hazard Material Safety Data Sheets Acute rating from U.S. EPA product label U.S. NTP Acute Toxicity Studies View Studies Cholinesterase Inhibitor	Ib, Highly Hazardous Not Listed Not Available Highly Toxic Not Acutely Toxic to Highly Toxic Yes
2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.

Cancer Information	Carbofuran
IARC Carcinogens U.S. NTP Carcinogens California Prop 65 Known Carcinogens U.S. EPA Carcinogens TRI Carcinogen	Not Listed Not Listed Not Listed Not Likely Not Listed

Endocrine Disruption	Carbofuran
Illinois EPA list Keith list Colborn list Benbrook list Danish Inert list EU list	Not listed Not listed Not listed Not listed Not listed Yes

Reproductive and Developmental Toxicity	Carbofuran
CA Prop 65 Developmental Toxin U.S. TRI Developmental Toxin CA Prop 65 Female Reproductive Toxin CA Prop 65 Male Reproductive Toxin U.S. TRI Reproductive Toxin	Not Listed Not Listed Not Listed Not Listed Not Listed

Chemicals of Special Concern	Carbofuran
PAN Bad Actors PAN Dirty Dozen list	Yes

Water Pollution Potential and Criteria for Carbofuran

Water Pollution Potential
PAN Ground Water Contaminant Rating	Potential

Physical Property Data Related to Water Contamination Potential
Water Solubility (Avg, mg/L) Adsorption Coefficient (Koc) Hydrolysis Half-life (Avg, Days) Aerobic Soil Half-life (Avg, Days) Anaerobic Soil Half-life (Avg, Days)	351.0 25.0 18.0 22.0 20.0

Water Standards and Criteria
U.S. National Drinking Water Standards and Health Criteria	�g/L unless noted
Maximum Contaminant Level (MCL)	40.0
Maximum Contaminant Level Goal (MCLG)	40.0
One Day Exposure Health Advisory Level
Ten Day Exposure Health Advisory Level
Lifetime Exposure Health Advisory Level
Reference Dose	0.06 (�g/kg/day)
U.S. Drinking Water Equivalent Level
Concentration with Lifetime Cancer Risk of 1 in 10,000

Canada Drinking Water Standards and Criteria	�g/L unless noted
Maximum Acceptable Concentration (MAC)	90.0
Interim Maximum Acceptable Concentration (IMAC)
Aesthetic Objectives

WHO Water Quality Criteria
Concentration (μg/l unless otherwise noted)	7.0

Canadian Water Quality Guidelines for the Protection of Aquatic Life	�g/L unless noted
Fresh Water Guidelines	1.8	Notes: i
Salt Water Guidelines

Canadian Water Quality Guidelines for the Protection of Agricultural Water Uses	�g/L unless noted
Irrigation Water Guidelines
Livestock Water Guidelines	45

Regulatory Information for Carbofuran

International Regulatory Status
Registration in Selected Countries	Registration in Selected Countries: Carbofuran

UNEP Persistent Organic Pollutant (POP) UNEP Prior Informed Consent Chemical (PIC) WHO Obsolete Pesticide	Yes Not Listed

U.S. and California Regulatory Status
U.S. EPA Registered U.S. EPA Hazardous Air Pollutant U.S. EPA Minimum Risk Pesticide (25b list) CA Registered CA Groundwater Contaminant CA Toxic Air Contaminant	Yes Not Listed No Yes Potential In Evaluation

Maximum Tolerance and Residue Levels
Codex Alimentarius (UN FAO Maximum Residue Limits) U.S. Maximum Tolerance Levels European Union Maximum Residue Levels	Go to web site Go to web site Go to web site

Ecotoxicity for Carbofuran

Note! Information for many chemicals is incomplete and may not be fully representative of effects on the environment. Why? Click on underlined terms for definitions and additional information.

Aquatic Ecotoxicity

Organism Group	Effects Noted
All Toxic Effects for Organism Group
Amphibians	Growth, Mortality
Annelida	Behavior, Histology, Intoxication, Mortality, Physiology, Population
AquaticPlants	Biochemistry, Growth, Morphology, Mortality, Physiology, Population
Crustaceans	Accumulation, Behavior, Biochemistry, Development, Enzyme(s), Growth, Intoxication, Mortality, Physiology, Population
Fish	Accumulation, Behavior, Biochemistry, Cell(s), Development, Enzyme(s), Feeding Behavior, Genetics, Growth, Histology, Hormone(s), Intoxication, Morphology, Mortality, No Effect Coded, Physiology, Population, Reproduction
Insects	Behavior, Development, Enzyme(s), Intoxication, Mortality, Population
Molluscs	Accumulation, Biochemistry, Development, Enzyme(s), Growth, Intoxication, Mortality, Population
NematodesandFlatworms	Population
Phytoplankton	Accumulation, Biochemistry, Cell(s), Enzyme(s), Growth, Mortality, Physiology, Population
TerrestrialPlants	Accumulation, Growth, Morphology, Population
Zooplankton	Behavior, Biochemistry, Enzyme(s), Feeding Behavior, Intoxication, Mortality, Population, Reproduction
~ Un-Assigned	Accumulation, Enzyme(s), Feeding Behavior, Growth, Mortality, Population
View All Aquatic Ecotoxicity Studies and References

Organism Group	Average Acute Toxicity	Acute Toxicity Range
Summary of Acute Toxicity for Organism Group
Amphibians	Slightly Toxic	Not Acutely Toxic to Slightly Toxic
Annelida	Moderately Toxic	Moderate Toxicity
Crustaceans	Highly Toxic	Moderate to Very High Toxicity
Fish	Moderately Toxic	Moderate to Very High Toxicity
Insects	Highly Toxic	Moderate to Very High Toxicity
Molluscs	Moderately Toxic	Moderate Toxicity
Phytoplankton	Slightly Toxic	Slight Toxicity
Zooplankton	Moderately Toxic	Slight to Very High Toxicity
~ Un-Assigned	Highly Toxic	Highly Toxic
View All Acute Summaries

Terrestrial Ecotoxicity

Organism Group	Average Acute Toxicity	Acute Toxicity Range
Summary of Acute Toxicity for Organism Group
Honeybees	Highly Toxic	Highly Toxic
Note: Population-level effects on honeybees may occur even if a pesticide has low acute toxicity. For example, certain pesticides interfere with honeybee reproduction, ability to navigate, or temperature regulation, any of which can have an effect on long-term survival of honeybee colonies. The neonicotinoids, pyrethroids and keto-enol pesticides are some types of pesticides causing one or more of these effects.

Honeybee Chronic Toxicity
Sorry, no honeybee chronic toxicity data available for this chemical. Try related chemicals.

Related Chemicals for Carbofuran

CAS Number	Relation	Reason	Chemical Name	Chem Detail	Registration	Symptoms	California Use	Chem Use Type	U.S. EPA Reg	PAN Bad Actor
1563-66-2	Parent	P	Carbofuran	View	View	View	View	Insecticide, Nematicide	Yes	Yes
16655-82-6	Related	5a	3-hydroxycarbofuran	View	View	View	View	Breakdown product	No	Yes
16709-30-1	Related	5a	3-ketocarbofuran	View	View	View	View	Breakdown product	No	Not Listed
17781-16-7	Related	5a	3-ketocarbofuran phenol	View	View	View	View	Breakdown product	No	Not Listed
1563-38-8	Related	5a	Carbofuran phenol	View	View	View	View	Breakdown product	No	Not Listed

Working with the Information on this Page

Click on underlined terms for definitions or go to the Pesticide Tutorial overview page.

Any underlined term with a book icon has additional information.

* Data marked with an asterisk indicates that this chemical is not explicitly listed on the corresponding list. Instead, it belongs to a group of chemicals that IS designated on the list. For example, if an agency assigns a classification of reproductive toxicant to "mercury compounds", that classification is applied to all mercury compounds in the PAN Pesticide database, which are then marked with an asterisk.

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Citation: Kegley, S.E., Hill, B.R., Orme S., Choi A.H., PAN Pesticide Database, Pesticide Action Network, North America (San Francisco, CA, 2010), http:www.pesticideinfo.org. © 2000-2010 Pesticide Action Network, North America. All rights reserved.

PAN Pesticides Database - Chemicals

Carbofuran - Identification, toxicity, use, water pollution potential, ecological toxicity and regulatory information

Chemical Identification and Use for Carbofuran

Basic Identification Information About This Chemical

Additional Resources About This Chemical Class and Use Type

Historical Use of this Chemical

Other Names for this ChemicalAbout Chemical Synonyms

Products Containing This Chemical

Signs and Symptoms of Carbofuran Poisoning

NOTE! There may be other diseases and chemicals that have similar symptoms.

If you have a poisoning emergency in the United States call 1-800-222-1222.If the victim has collapsed or is unconscious, call 911.

Carbofuran is a high toxicity Carbamate compound.

Report a Poisoning

Symptoms of Poisoning with high toxicity Carbamate Compounds

Treatment for high toxicity Carbamate Poisoning

Symptoms of Carbofuran Exposure from the International Chemical Safety Cards (ICSC)

Report a Poisoning

NOTE! PREVENT DISPERSION OF DUST! STRICT HYGIENE! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN!

Route of Exposure

Symptoms

First Aid

Toxicity Information for Carbofuran

Summary Toxicity Information

Additional Resources about the Toxicity of this Chemical

Detailed Toxicity Information

Acute Toxicity 2

Cancer Information

Endocrine Disruption

Reproductive and Developmental Toxicity

Chemicals of Special Concern

Water Pollution Potential and Criteria for Carbofuran

Water Pollution Potential

Physical Property Data Related to Water Contamination Potential

Water Standards and Criteria

U.S. National Drinking Water Standards and Health Criteria

Canada Drinking Water Standards and Criteria

WHO Water Quality Criteria

Canadian Water Quality Guidelines for the Protection of Aquatic Life

Canadian Water Quality Guidelines for the Protection of Agricultural Water Uses

Regulatory Information for Carbofuran

International Regulatory Status

U.S. and California Regulatory Status

Maximum Tolerance and Residue Levels

Ecotoxicity for Carbofuran

Aquatic Ecotoxicity

All Toxic Effects for Organism Group

Summary of Acute Toxicity for Organism Group

Terrestrial Ecotoxicity

Summary of Acute Toxicity for Organism Group

Honeybee Chronic Toxicity

Related Chemicals for Carbofuran

Other Names for this Chemical
About Chemical Synonyms

If you have a poisoning emergency in the United States call 1-800-222-1222.
If the victim has collapsed or is unconscious, call 911.

Acute Toxicity ²