PAN Pesticides Database - Chemicals

Chlordecone - Identification, toxicity, use, water pollution potential, ecological toxicity and regulatory information

Note: See Working with the Information on this Page section below for important notes about this data.

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Identifying information, including synonyms, ID numbers, use type, chemical classification, a link to a list of all products containing this chemical and a list of the top crops this pesticide is used on in California.
Signs and symptoms of poisoning, first aid, and links to treatment information for this chemical.
Link to information on toxicity to humans, including carcinogenicity, reproductive and developmental toxicity, neurotoxicity, and acute toxicity.
Links to world-wide registration status as well as regulatory information for the U.S. and California.
Water quality standards and physical properties affecting water contamination potential.
Toxicity to aquatic organisms.
List of chemicals in the same family, including breakdown products, salts, esters, isomers, and other derivatives.
 

Chemical Identification and Use for Chlordecone

Basic Identification Information About This Chemical
Chemical Name: Chlordecone
CAS Number: 143-50-0
U.S. EPA PC Code: 027701
CA DPR Chem Code: 347
Molecular Weight: 490.68
Molecular Structure:
Use Type: Insecticide
Chem Class: Organochlorine
View Related Chemicals
 
Additional Resources About This Chemical Class and Use Type
Historical Use of this Chemical
Top five crops and sites for this pesticide in California
Structural Pest Control  
View All Crops and Sites
 
Other Names for this Chemical
About Chemical Synonyms
(US EPA PC Code ) , 027701 (US EPA PC Code Text ) , 1,1a,3,3a,4,5,5,5a,5b,6-Decachlorooctahydro-1,3,4-metheno-2H-cyclobuta[cd]pentalen-2-one , 1189 , 143-50-0 (CAS number) , 143500 , 143500 (CAS number without hyphens) , 347 (CA DPR Chem Code) ) , Chlordecone , CHLORDECONE (CA DPR Chem Code Text ) , Chlordecone (Kepone ) , Chlordecone (Kepone) , Chlordecone Kepone , Decachloroketone , Decachlorooctahydro-1,3,4-metheno-2H-cyclobuta(cd)pentalen-2-one , Decachloropentacyclo(5.3.0.0.0.0 2,6,4,10,5,9)decane-3-one , Decachlorotetracyclodecanone , ENT 16391 , GC 1189 , General Chemicals 1189 , Kepone , Kepone-2-one, decachlorooctahydro- , Merex
 
Products Containing This Chemical
Current and historic U.S. registered products
View U.S. Products All Products Currently Registered Products
 

Signs and Symptoms of Chlordecone Poisoning

NOTE! There may be other diseases and chemicals that have similar symptoms.

If you have a poisoning emergency in the United States call 1-800-222-1222.
If the victim has collapsed or is unconscious, call 911.

Chlordecone is a Organochlorine compound.

Report a Poisoning

Symptoms of Poisoning with Organochlorine Compounds
Find Products Containing this Chemical

- Hypersensitive to stimulation, sensation of prickling, tingling or creeping on skin.
- Headache, dizziness, nausea, vomiting, incoordination, tremor, mental confusion, hyperexcitable state.
- In severe cases: convulsions, seizures, coma and respiratory depression.

Source for Group Symptoms: Recognition and Management of Pesticide Poisoning, 5th edition, U.S. EPA, Chapter 6.

Treatment for Organochlorine Poisoning

See: Recognition and Management of Pesticide Poisoning, 5th edition, U.S. EPA, Chapter 6, page 58.

 
Symptoms of Chlordecone Exposure from the International Chemical Safety Cards (ICSC)

Report a Poisoning

View full ICSC Cards: English   Español   Française   Chinese   Dutch   Finnish   German   Hungarian   Japanese   Swahili   Thai   Urdu  
NOTE! AVOID ALL CONTACT! AVOID EXPOSURE OF (PREGNANT) WOMEN!
General First Aid: IN ALL CASES CONSULT A DOCTOR!

Route of Exposure

Symptoms

First Aid

Inhalation Loss of movement co-ordination. Headache. Tremor. Weakness. Fresh air rest. Refer for medical attention.
Skin MAY BE ABSORBED! Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.
Eyes First rinse with plenty of water for several minutes (remove contact lenses if easily possible) then take to a doctor.
Ingestion (See Inhalation). Give a slurry of activated charcoal in water to drink. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention. See Notes.
Notes for ICSC Information
Carrier solvents used in commercial formulations may change physical and toxicological properties. Do NOT take working clothes home.
 

Toxicity Information for Chlordecone

  Note: Information for many chemicals is incomplete and may not be fully representative of effects on humans. Why?

Summary Toxicity Information

PAN Bad Actor
Chemical
1
Acute
Toxicity
2
Carcinogen Cholinesterase
Inhibitor
Ground
Water Contaminant
Developmental or
Reproductive Toxin
Endocrine
Disruptor
Moderate
No
Suspected
 
Indicates high toxicity in the given toxicological category. Indicates no available weight-of-the-evidence summary assessment. For additional information on toxicity from scientific journals or registration documents, see the "Additional Resources for Toxicity " section of the chemical detail page.
1. PAN Bad Actors are chemicals that are one or more of the following: highly acutely toxic, cholinesterase inhibitor, known/probable carcinogen, known groundwater pollutant or known reproductive or developmental toxicant. NOTE! Because there are no authoritative lists of Endocrine Disrupting (ED) chemicals, EDs are not yet considered PAN Bad Actor chemicals.
2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.

Detailed Toxicity Information

This Chemical
Parent Chemical 
Acute Toxicity 2
Chlordecone Mirex
WHO Acute Hazard
TRI Acute Hazard
Material Safety Data Sheets
Acute rating from U.S. EPA product label
U.S. NTP Acute Toxicity Studies
      View Studies
Cholinesterase Inhibitor
Not Listed
Not Listed
Not Available
No Consensus Value
Moderately Toxic

No
Not Listed
Not Listed
Not Available
Moderately Toxic
Moderately Toxic

No
2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.
 
Cancer Information
Chlordecone Mirex
IARC Carcinogens
U.S. NTP Carcinogens
California Prop 65 Known Carcinogens
U.S. EPA Carcinogens
TRI Carcinogen
2B, Possible
Reasonably Anticipated
Yes
Not Listed
Not Listed
2B, Possible
Reasonably Anticipated
Yes
Not Listed
Not Listed
 
Endocrine Disruption
Chlordecone Mirex
Illinois EPA list
Keith list
Colborn list
Benbrook list
Danish Inert list
EU list
Known
Not Listed
Yes
Not Listed
Not listed
Yes
Probable
Yes
Yes
Not Listed
Not listed
Yes
 
Reproductive and Developmental Toxicity
Chlordecone Mirex
CA Prop 65 Developmental Toxin
U.S. TRI Developmental Toxin
CA Prop 65 Female Reproductive Toxin
CA Prop 65 Male Reproductive Toxin
U.S. TRI Reproductive Toxin
Yes
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
 
Chemicals of Special Concern
Chlordecone Mirex
PAN Bad Actors
PAN Dirty Dozen list
Yes
Yes
 

Water Pollution Potential and Criteria for Chlordecone

Water Pollution Potential

This Chemical
Parent Chemical
  Chlordecone Mirex
PAN Ground Water Contaminant Rating Insufficient Data Insufficient Data
 
Physical Property Data Related to Water Contamination Potential
Water Solubility (Avg, mg/L)
Adsorption Coefficient (Koc)
Hydrolysis Half-life (Avg, Days)
Aerobic Soil Half-life (Avg, Days)
Anaerobic Soil Half-life (Avg, Days)
3.00
2,500
-
450.0
-
 
 

Sorry, no water quality standards or criteria have been established for this chemical by the U.S. or Canadian governments; however, there may be criteria established for related chemicals.

 

Regulatory Information for Chlordecone

International Regulatory Status

This Chemical
Parent Chemical 
 
UNEP Persistent Organic Pollutant (POP)
UNEP Prior Informed Consent Chemical (PIC)
WHO Obsolete Pesticide
Reviewed

Yes
Yes

Yes
 

U.S. and California Regulatory Status

U.S. EPA Registered
U.S. EPA Hazardous Air Pollutant
U.S. EPA Minimum Risk Pesticide (25b list)

CA Registered
CA Groundwater Contaminant
CA Toxic Air Contaminant
No
Not Listed
No

No
Not Listed
Not Listed
No
Not Listed
No

No
Not Listed
Not Listed
 

Maximum Tolerance and Residue Levels

Codex Alimentarius
   (UN FAO Maximum Residue Limits)
U.S. Maximum Tolerance Levels
European Union Maximum Residue Levels
Go to web site

Go to web site

Go to web site
 

Ecotoxicity for Chlordecone

Note! Information for many chemicals is incomplete and may not be fully representative of effects on the environment. Why? Click on underlined terms for definitions and additional information.

Aquatic Ecotoxicity

All Toxic Effects for Organism Group
Organism Group Effects Noted
Amphibians Mortality
Annelida Behavior, Mortality
Crustaceans Accumulation, Behavior, Development, Growth, Mortality, No Effect Coded, Physiology
Fish Accumulation, Behavior, Biochemistry, Development, Enzyme(s), Growth, Histology, Morphology, Mortality, Physiology, Reproduction
Insects Accumulation, Development, Growth, Intoxication, Mortality
Molluscs Accumulation, Growth, Morphology, Mortality
Phytoplankton Accumulation, Growth, Physiology, Population
Zooplankton Accumulation, Behavior, Biochemistry, Development, Genetics, Growth, Intoxication, Mortality, Reproduction
View All Aquatic Ecotoxicity Studies and References
 
Summary of Acute Toxicity for Organism Group
Organism Group Average Acute Toxicity Acute Toxicity Range
Crustaceans Highly Toxic Moderate to Very High Toxicity
Fish Highly Toxic High to Very High Toxicity
Insects Highly Toxic Highly Toxic
Molluscs Moderately Toxic Moderate Toxicity
Zooplankton Highly Toxic High to Very High Toxicity
View All Acute Summaries
 

Terrestrial Ecotoxicity

Summary of Acute Toxicity for Organism Group

Sorry, no honeybee acute toxicity data available for this chemical. Try related chemicals.

Note: Population-level effects on honeybees may occur even if a pesticide has low acute toxicity. For example, certain pesticides interfere with honeybee reproduction, ability to navigate, or temperature regulation, any of which can have an effect on long-term survival of honeybee colonies. The neonicotinoids, pyrethroids and keto-enol pesticides are some types of pesticides causing one or more of these effects.
Honeybee Chronic Toxicity

Sorry, no honeybee chronic toxicity data available for this chemical. Try related chemicals.

Related Chemicals for Chlordecone

CAS Number Relation Reason Chemical Name Chem Detail Symptoms California Use Chem Use Type U.S. EPA Reg PAN Bad Actor
2385-85-5 Parent P Mirex View View View Insecticide, Flame retardant No Yes
143-50-0 Related 2 Chlordecone View View View Insecticide No Yes
13560-89-9 Related 2 Dechlorane plus 25 View View View No Not Listed
 
Working with the Information on this Page

Click on underlined terms for definitions or go to the Pesticide Tutorial overview page.

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* Data marked with an asterisk indicates that this chemical is not explicitly listed on the corresponding list. Instead, it belongs to a group of chemicals that IS designated on the list. For example, if an agency assigns a classification of reproductive toxicant to "mercury compounds", that classification is applied to all mercury compounds in the PAN Pesticide database, which are then marked with an asterisk.

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