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Hexazinone - Identification, toxicity, use, water pollution potential, ecological toxicity and regulatory information

Note: See Working with the Information on this Page section below for important notes about this data.

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Chemical ID
 Identifying information, including synonyms, ID numbers, use type, chemical classification, a link to a list of all products containing this chemical and a list of the top crops this pesticide is used on in California.
Poisoning Symptoms
 Signs and symptoms of poisoning, first aid, and links to treatment information for this chemical.
Toxicity
 Link to information on toxicity to humans, including carcinogenicity, reproductive and developmental toxicity, neurotoxicity, and acute toxicity.
Regulatory
 Links to world-wide registration status as well as regulatory information for the U.S. and California.
Water
 Water quality standards and physical properties affecting water contamination potential.
Ecotoxicity
 Toxicity to aquatic organisms.
Related Chems
 List of chemicals in the same family, including breakdown products, salts, esters, isomers, and other derivatives.
 

Chemical Identification and Use for Hexazinone
Basic Identification Information About This Chemical
Chemical Name: Hexazinone
CAS Number: 51235-04-2
U.S. EPA PC Code: 107201
CA DPR Chem Code: 1871
Molecular Weight: 252.31
Molecular Structure:
Use Type: Herbicide
Chem Class: Triazinone
View Related Chemicals
 
Additional Resources About This Chemical Class and Use Type

See the Global Pesticide Resources page for many additional links.
Historical Use of this Chemical
Top five crops and sites for this pesticide in California
Alfalfa for Forage   Forests   Right of Way   Landscape   Carrots  
View All Crops and Sites
 
Other Names for this Chemical
About Chemical Synonyms
01871 (CA DPR Chem Code Text) , 01871 (CA DPR Chem Code) , 1,3,5-Triazine-2,4(1H,3H)dione, 3-cyclohexyl-6-(dimethylamino)-1-methyl- , 107201 (US EPA PC Code Text) , 107201 (US EPA PC Code) , 1871 (CA DPR Chem Code) , 1871 (CA DPR Chem Code) , 3-Cyclohexyl-6-(dimethylamino)-1-methyl-1,3,5-triazine-2,4(1H,3H)-dione , 3-Cyclohexyl-6-(dimethylamino)-1-methyl-s-triazine-2,4(1H,3H)-dione , 3-cyclohexyl-6-dimethylamino-1-methyl-1,3,5-triazine-2,4-(1H,3H)-dione , 51235-04-2 (CAS number) , 51235042 , 51235042 (CAS number without hyphens) , 633 (PDP Code) , DPX 3674 , H 12156 , Heksazinon , Hexazinon , Hexazinona , Hexazinone , Hexazinone , Hexazinone (ANSI) , Velpar Herbicide , Velpar L
 
Products Containing This Chemical
Current and historic U.S. registered products
View U.S. Products All Products Currently Registered Products
 

Signs and Symptoms of Hexazinone Poisoning

NOTE! There may be other diseases and chemicals that have similar symptoms.

If you have a poisoning emergency in the United States call 1-800-222-1222.
If the victim has collapsed or is unconscious, call 911.

Sorry! No symptoms for this chemical or chemical group are available. See related chemicals for possible additional information.
 
 

Toxicity Information for Hexazinone

  Note: Information for many chemicals is incomplete and may not be fully representative of effects on humans. Why?

Summary Toxicity Information

PAN Bad Actor
Chemical 1 		Acute
Toxicity 2 		Carcinogen Cholinesterase
Inhibitor 		Ground
Water Contaminant 		Developmental or
Reproductive Toxin 		Endocrine
Disruptor
Unclassifiable No
 
Indicates high toxicity in the given toxicological category. Indicates no available weight-of-the-evidence summary assessment. For additional information on toxicity from scientific journals or registration documents, see the "Additional Resources for Toxicity " section of the chemical detail page.
1. PAN Bad Actors are chemicals that are one or more of the following: highly acutely toxic, cholinesterase inhibitor, known/probable carcinogen, known groundwater pollutant or known reproductive or developmental toxicant. NOTE! Because there are no authoritative lists of Endocrine Disrupting (ED) chemicals, EDs are not yet considered PAN Bad Actor chemicals.
2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.

Additional Resources about the Toxicity of this Chemical

See the Global Pesticide Resources page for many additional links.

Detailed Toxicity Information
Acute Toxicity 2
 Hexazinone
WHO Acute Hazard
TRI Acute Hazard
Material Safety Data Sheets
Acute rating from U.S. EPA product label
U.S. NTP Acute Toxicity Studies
      View Studies
Cholinesterase Inhibitor		 III, Slightly Hazardous
Not Listed
Not Available
Highly Toxic
No NTP Studies

No
2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.
 
Cancer Information
 Hexazinone
IARC Carcinogens
U.S. NTP Carcinogens
California Prop 65 Known Carcinogens
U.S. EPA Carcinogens
TRI Carcinogen		 Not Listed
Not Listed
Not Listed
D, Unclassifiable, ambiguous data
Not Listed
 
Endocrine Disruption
 Hexazinone
Illinois EPA list
Keith list
Colborn list
Benbrook list
Danish Inert list
EU list		 Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
 
Reproductive and Developmental Toxicity
 Hexazinone
CA Prop 65 Developmental Toxin
U.S. TRI Developmental Toxin
CA Prop 65 Female Reproductive Toxin
CA Prop 65 Male Reproductive Toxin
U.S. TRI Reproductive Toxin 		Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
 
Chemicals of Special Concern
 Hexazinone
PAN Bad Actors
PAN Dirty Dozen list		 Yes
Not Listed
 

Water Pollution Potential and Criteria for Hexazinone

Water Pollution Potential

PAN Ground Water Contaminant Rating Known
 
Physical Property Data Related to Water Contamination Potential
Water Solubility (Avg, mg/L)
Adsorption Coefficient (Koc)
Hydrolysis Half-life (Avg, Days)
Aerobic Soil Half-life (Avg, Days)
Anaerobic Soil Half-life (Avg, Days) 		29,800
640.0
56.0
222.0
232.0 		 
 

Water Standards and Criteria
U.S. National Drinking Water Standards and Health Criteria
 µg/L unless noted  
Maximum Contaminant Level (MCL) 0  
Maximum Contaminant Level Goal (MCLG)  
One Day Exposure Health Advisory Level 3,000  
Ten Day Exposure Health Advisory Level 2,000  
Lifetime Exposure Health Advisory Level 400.0  
Reference Dose 50.0 (µg/kg/day)  
U.S. Drinking Water Equivalent Level 2,000  
Concentration with Lifetime Cancer Risk of 1 in 10,000  
 

Regulatory Information for Hexazinone

International Regulatory Status
Registration in Selected Countries Registration in Selected Countries:
Hexazinone
 
UNEP Persistent Organic Pollutant (POP)
UNEP Prior Informed Consent Chemical (PIC)
WHO Obsolete Pesticide		 Not Listed
Not Listed
Not Listed
 

U.S. and California Regulatory Status
U.S. EPA Registered
U.S. EPA Hazardous Air Pollutant
U.S. EPA Minimum Risk Pesticide (25b list)

CA Registered
CA Groundwater Contaminant
CA Toxic Air Contaminant 		Yes
Not Listed
No

Yes
Potential
Not Listed
 

Maximum Tolerance and Residue Levels
Codex Alimentarius
   (UN FAO Maximum Residue Limits)
U.S. Maximum Tolerance Levels
European Union Maximum Residue Levels 		Go to web site

Go to web site
Go to web site
 

Ecotoxicity for Hexazinone

Note! Information for many chemicals is incomplete and may not be fully representative of effects on the environment. Why? Click on underlined terms for definitions and additional information.

Aquatic Ecotoxicity
All Toxic Effects for Organism Group
Organism Group Effects Noted
Amphibians Growth, Intoxication, Mortality
Annelida Population
AquaticPlants Biochemistry, Growth, Morphology, Physiology, Population
Crustaceans Mortality
Fish Accumulation, Biochemistry, Enzyme(s), Feeding Behavior, Growth, Hormone(s), Morphology, Mortality, No Effect Coded, Physiology
Insects Behavior, Mortality, Population
Molluscs Mortality
Phytoplankton Biochemistry, Ecosystem Process, Physiology, Population
Zooplankton Growth, Intoxication, Mortality, Population
~ Un-Assigned Biochemistry, Population
View All Aquatic Ecotoxicity Studies and References
 
Summary of Acute Toxicity for Organism Group
Organism Group Average Acute Toxicity Acute Toxicity Range
Crustaceans Not Acutely Toxic Not Acutely Toxic to Slightly Toxic
Fish Not Acutely Toxic Not Acutely Toxic to Slightly Toxic
Insects Slightly Toxic Slight Toxicity
Molluscs Not Acutely Toxic Not Acutely Toxic
Zooplankton Not Acutely Toxic Not Acutely Toxic to Slightly Toxic
View All Acute Summaries
 

Terrestrial Ecotoxicity
Summary of Acute Toxicity for Organism Group
Organism Group Average Acute Toxicity Acute Toxicity Range
HoneybeesSlightly ToxicSlightly Toxic
Note: Population-level effects on honeybees may occur even if a pesticide has low acute toxicity. For example, certain pesticides interfere with honeybee reproduction, ability to navigate, or temperature regulation, any of which can have an effect on long-term survival of honeybee colonies. The neonicotinoids, pyrethroids and keto-enol pesticides are some types of pesticides causing one or more of these effects.
Honeybee Chronic Toxicity

Sorry, no honeybee chronic toxicity data available for this chemical. Try related chemicals.

Related Chemicals for Hexazinone
CAS Number Relation Reason Chemical Name Chem Detail Registration Symptoms California Use Chem Use Type U.S. EPA Reg PAN Bad Actor
51235-04-2 Parent P Hexazinone View View View View Herbicide Yes Yes
Related 5a 2-hydroxycyclohexyl hexazinone View View View View Breakdown product No Not Listed
Related 5a Decyclohexyl-4-hydroxy hexazinone View View View View Breakdown product No Not Listed
Related 5a Monomethyl hexazinone View View View View Breakdown product No Not Listed
 
Working with the Information on this Page

Click on underlined terms for definitions or go to the Pesticide Tutorial overview page.

Any underlined term with a book icon has additional information.

* Data marked with an asterisk indicates that this chemical is not explicitly listed on the corresponding list. Instead, it belongs to a group of chemicals that IS designated on the list. For example, if an agency assigns a classification of reproductive toxicant to "mercury compounds", that classification is applied to all mercury compounds in the PAN Pesticide database, which are then marked with an asterisk.

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Citation: Kegley, S.E., Hill, B.R., Orme S., Choi A.H., PAN Pesticide Database, Pesticide Action Network, North America (San Francisco, CA, 2010), http:www.pesticideinfo.org.
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