PAN Pesticides Database - Chemicals

Epichlorohydrin - Identification, toxicity, use, water pollution potential, ecological toxicity and regulatory information

Note: See Working with the Information on this Page section below for important notes about this data.

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Identifying information, including synonyms, ID numbers, use type, chemical classification, a link to a list of all products containing this chemical and a list of the top crops this pesticide is used on in California.
Signs and symptoms of poisoning, first aid, and links to treatment information for this chemical.
Link to information on toxicity to humans, including carcinogenicity, reproductive and developmental toxicity, neurotoxicity, and acute toxicity.
Links to world-wide registration status as well as regulatory information for the U.S. and California.
Water quality standards and physical properties affecting water contamination potential.
Toxicity to aquatic organisms.
List of chemicals in the same family, including breakdown products, salts, esters, isomers, and other derivatives.

Chemical Identification and Use for Epichlorohydrin

Basic Identification Information About This Chemical
Chemical Name: Epichlorohydrin
CAS Number: 106-89-8
U.S. EPA PC Code: 097201 (Same as US EPA PC Code 600503)
600503 (Same as US EPA PC Code 097201)
CA DPR Chem Code: 1927
Molecular Weight: 92.53
Use Type: Chemical intermediate , Dye , Fungicide , Insecticide , Microbiocide , Paints, coatings, resins , Polymer production , Solvent
Chem Class:
View Related Chemicals
Additional Resources About This Chemical Class and Use Type
Other Names for this Chemical
About Chemical Synonyms
(US EPA PC Code (Same as US EPA PC Code 600503)) , (Chloromethyl)ethylene oxide , (Chloromethyl)oxirane , .alpha.-Epichlorohydrin , .gamma.-Chloropropylene oxide , 097201 (US EPA PC Code Text (Same as US EPA PC Code 600503)) , 1,2-Epoxy-3-chloropropane , 1-Chloro-2,3-epoxy-propane , 1-Chloro-2,3-epoxypropane , 1-Chloropropyl epoxide , 106-89-8 (CAS number) , 106898 , 106898 (CAS number without hyphens) , 1927 (CA DPR Chem Code) ) , 2,3-Epoxypropyl chloride , 3-Chloro-1,2-epoxypropane , 3-Chloro-1,2-propylene oxide , 3-Chloropropene-1,2-oxide , 3-Chloropropylene oxide , 600503 (US EPA PC Code alt.) , 600503 (US EPA PC Code Text (Same as US EPA PC Code 600503)) , 800022 (US EPA PC Code Text (Same as US EPA PC Code 600503)) , Allyl chloride oxide , Chloromethyloxiran , ECH , Epi , Epichlorohydrin , Epichlorohydrin (NO INERT USE) , EPICHLOROHYDRIN (CA DPR Chem Code Text ) , Epichlorohydrin (l-Chloro-2,3-epoxypropane) , Ethylene oxide, (chloromethyl)- , Glycerol epichlorohydrin , Glycidyl chloride , Oxirane, (chloromethyl)- , Propane, 1-chloro-2,3-epoxy- , Propylene oxide, 3-chloro- , SKEKHG , Yes (US EPA PC Code (Same as US EPA PC Code 600503)) , Yes (US EPA PC Code (Same as US EPA PC Code 600503))
Products Containing This Chemical
Current and historic U.S. registered products
View U.S. Products All Products Currently Registered Products

Signs and Symptoms of Epichlorohydrin Poisoning

NOTE! There may be other diseases and chemicals that have similar symptoms.

If you have a poisoning emergency in the United States call 1-800-222-1222.
If the victim has collapsed or is unconscious, call 911.

Symptoms of Epichlorohydrin Exposure from the International Chemical Safety Cards (ICSC)

Report a Poisoning

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Route of Exposure


First Aid

Inhalation Burning sensation. Cough. Headache. Laboured breathing. Nausea. Shortness of breath. Sore throat. Vomiting. Tremor. Symptoms may be delayed (see Notes). Fresh air rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.
Skin MAY BE ABSORBED! Redness. skin burns. Serious Burning sensation. Pain. Blisters. Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention.
Eyes Redness. Pain. loss of vision. Permanent Severe deep burns. First rinse with plenty of water for several minutes (remove contact lenses if easily possible) then take to a doctor.
Ingestion Abdominal cramps. Burning sensation in the throat and chest. Diarrhoea. Headache. Nausea. Shock or collapse. Sore throat. Vomiting. Rinse mouth. Do NOT induce vomiting. Give plenty of water to drink. Rest. Refer for medical attention.
Notes for ICSC Information
Other melting points: -25.6 C and -57C. Depending on the degree of exposure periodic medical examination is indicated. The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. Immediate administration of an appropriate spray by a doctor or a person authorized by him/her should be considered. The odour warning when the exposure limit value is exceeded is insufficient. Do NOT take working clothes home.

Toxicity Information for Epichlorohydrin

  Note: Information for many chemicals is incomplete and may not be fully representative of effects on humans. Why?

Summary Toxicity Information

PAN Bad Actor
Carcinogen Cholinesterase
Water Contaminant
Developmental or
Reproductive Toxin
Indicates high toxicity in the given toxicological category. Indicates no available weight-of-the-evidence summary assessment. For additional information on toxicity from scientific journals or registration documents, see the "Additional Resources for Toxicity " section of the chemical detail page.
1. PAN Bad Actors are chemicals that are one or more of the following: highly acutely toxic, cholinesterase inhibitor, known/probable carcinogen, known groundwater pollutant or known reproductive or developmental toxicant. NOTE! Because there are no authoritative lists of Endocrine Disrupting (ED) chemicals, EDs are not yet considered PAN Bad Actor chemicals.
2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.

Detailed Toxicity Information

Acute Toxicity 2
WHO Acute Hazard
TRI Acute Hazard
Material Safety Data Sheets
Acute rating from U.S. EPA product label
U.S. NTP Acute Toxicity Studies
      View Studies
Cholinesterase Inhibitor
Not Listed
Not Listed
Not Available
No Consensus Value
Slightly to Moderately Toxic

2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.
Cancer Information
IARC Carcinogens
U.S. NTP Carcinogens
California Prop 65 Known Carcinogens
U.S. EPA Carcinogens
TRI Carcinogen
2A, Probable
Reasonably Anticipated
B2, Probable
Not Listed
Endocrine Disruption
Illinois EPA list
Keith list
Colborn list
Benbrook list
Danish Inert list
EU list
Not listed
Not listed
Not listed
Not listed
Not listed
Reproductive and Developmental Toxicity
CA Prop 65 Developmental Toxin
U.S. TRI Developmental Toxin
CA Prop 65 Female Reproductive Toxin
CA Prop 65 Male Reproductive Toxin
U.S. TRI Reproductive Toxin
Not Listed
Not Listed
Not Listed
Not Listed
Chemicals of Special Concern
PAN Bad Actors
PAN Dirty Dozen list
Not Listed

Water Pollution Potential and Criteria for Epichlorohydrin

Water Pollution Potential

PAN Ground Water Contaminant Rating Insufficient Data

Water Standards and Criteria

U.S. National Drinking Water Standards and Health Criteria
g/L unless noted  
Maximum Contaminant Level (MCL) 0 Notes: D2  
Maximum Contaminant Level Goal (MCLG) 0  
One Day Exposure Health Advisory Level 100.0  
Ten Day Exposure Health Advisory Level 100.0  
Lifetime Exposure Health Advisory Level  
Reference Dose 2.00 (g/kg/day)  
U.S. Drinking Water Equivalent Level 70.0  
Concentration with Lifetime Cancer Risk of 1 in 10,000 300.0  
WHO Water Quality Criteria
Concentration (μg/l unless otherwise noted) 0.4
Notes Notes: P

Regulatory Information for Epichlorohydrin

International Regulatory Status

UNEP Persistent Organic Pollutant (POP)
UNEP Prior Informed Consent Chemical (PIC)
WHO Obsolete Pesticide
Not Listed
Not Listed
Not Listed

U.S. and California Regulatory Status

U.S. EPA Registered
U.S. EPA Hazardous Air Pollutant
U.S. EPA Minimum Risk Pesticide (25b list)

CA Registered
CA Groundwater Contaminant
CA Toxic Air Contaminant

Not Listed

Maximum Tolerance and Residue Levels

Codex Alimentarius
   (UN FAO Maximum Residue Limits)
U.S. Maximum Tolerance Levels
European Union Maximum Residue Levels
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Ecotoxicity for Epichlorohydrin

Note! Information for many chemicals is incomplete and may not be fully representative of effects on the environment. Why? Click on underlined terms for definitions and additional information.

Aquatic Ecotoxicity

All Toxic Effects for Organism Group
Organism Group Effects Noted
Amphibians Genetics
Fish Mortality
Phytoplankton Population
Zooplankton Behavior, Intoxication, Mortality, Population
View All Aquatic Ecotoxicity Studies and References
Summary of Acute Toxicity for Organism Group
Organism Group Average Acute Toxicity Acute Toxicity Range
Fish Slightly Toxic Slight Toxicity
Zooplankton Slightly Toxic Slight Toxicity
View All Acute Summaries

Terrestrial Ecotoxicity

Summary of Acute Toxicity for Organism Group

Sorry, no honeybee acute toxicity data available for this chemical. Try related chemicals.

Note: Population-level effects on honeybees may occur even if a pesticide has low acute toxicity. For example, certain pesticides interfere with honeybee reproduction, ability to navigate, or temperature regulation, any of which can have an effect on long-term survival of honeybee colonies. The neonicotinoids, pyrethroids and keto-enol pesticides are some types of pesticides causing one or more of these effects.
Honeybee Chronic Toxicity

Sorry, no honeybee chronic toxicity data available for this chemical. Try related chemicals.

Related Chemicals for Epichlorohydrin

CAS Number Relation Reason Chemical Name Chem Detail Symptoms California Use Chem Use Type U.S. EPA Reg PAN Bad Actor
106-89-8 Parent P Epichlorohydrin View View View Microbiocide, Fungicide, Insecticide No Yes
Working with the Information on this Page

Click on underlined terms for definitions or go to the Pesticide Tutorial overview page.

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* Data marked with an asterisk indicates that this chemical is not explicitly listed on the corresponding list. Instead, it belongs to a group of chemicals that IS designated on the list. For example, if an agency assigns a classification of reproductive toxicant to "mercury compounds", that classification is applied to all mercury compounds in the PAN Pesticide database, which are then marked with an asterisk.

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