PAN Pesticides Database - Chemicals

Chlorpyrifos-methyl - Identification, toxicity, use, water pollution potential, ecological toxicity and regulatory information

Note: See Working with the Information on this Page section below for important notes about this data.

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Identifying information, including synonyms, ID numbers, use type, chemical classification, a link to a list of all products containing this chemical and a list of the top crops this pesticide is used on in California.
Signs and symptoms of poisoning, first aid, and links to treatment information for this chemical.
Link to information on toxicity to humans, including carcinogenicity, reproductive and developmental toxicity, neurotoxicity, and acute toxicity.
Links to world-wide registration status as well as regulatory information for the U.S. and California.
Water quality standards and physical properties affecting water contamination potential.
Toxicity to aquatic organisms.
List of chemicals in the same family, including breakdown products, salts, esters, isomers, and other derivatives.
 

Chemical Identification and Use for Chlorpyrifos-methyl

Basic Identification Information About This Chemical
Chemical Name: Chlorpyrifos-methyl
CAS Number: 5598-13-0
5998-13-0
U.S. EPA PC Code: 059102
219300 (Old US EPA PC Code.)
CA DPR Chem Code: 2468
Molecular Weight: 322.53
Use Type: Insecticide
Chem Class: Organophosphorus
View Related Chemicals
 
Additional Resources About This Chemical Class and Use Type
 
Other Names for this Chemical
About Chemical Synonyms
(US EPA PC Code ) , (US EPA PC Code ) , 059102 (US EPA PC Code Text ) , 219300 (Old US EPA PC Code) , 219300 (US EPA PC Code Text ) , 235 (PDP Code) , 2468 (CA DPR Chem Code) ) , 5598-13-0 (CAS number) , 5598130 , 5598130 (CAS number without hyphens) , 5998-13-0 (CAS number) , 5998130 (CAS number without hyphens) , Chlormethylfos , Chlorpyiphos-methyl , Chlorpyrifos methyl , Chlorpyrifos-methyl , CHLORPYRIFOS-METHYL (CA DPR Chem Code Text ) , Chlorpyrifosmethyl , Chlorpyriphos methyl , chlorpyriphos-methyl , Clorpirifos-metilo , Dowco 214 , ENT 27520 , Kl?rpirifosz-metil , O,O-Dimethyl O-(3,5,6-trichloro-2-pyridinyl) ester phosphorothioic acid , O,O-Dimethyl O-(3,5,6-trichloro-2-pyridyl) phosophorothioate , OMS 1155 , Phosphorothioic acid, O,O-dimethyl O-(3,5,6-trichloro-2-pyridyl) ester , Reldan , Trichlormethylfos , Use code no. 059102
 
Products Containing This Chemical
Current and historic U.S. registered products
View U.S. Products All Products Currently Registered Products
 

Signs and Symptoms of Chlorpyrifos-methyl Poisoning

NOTE! There may be other diseases and chemicals that have similar symptoms.

If you have a poisoning emergency in the United States call 1-800-222-1222.
If the victim has collapsed or is unconscious, call 911.

Chlorpyrifos-methyl is a Organophosphorus compound.

Report a Poisoning

Symptoms of Poisoning with Organophosphorus Compounds
Find Products Containing this Chemical

- Excessive salivation, sweating, rhinorrhea and tearing.
- Muscle twitching, weakness, tremor, incoordination.
- Headache, dizziness, nausea, vomiting, abdominal cramps, diarrhea.
- Respiratory depression, tightness in chest, wheezing, productive cough, fluid in lungs.
- Pin-point pupils, sometimes with blurred or dark vision.
- Severe cases: seizures, incontinence, respiratory depression, loss of consciousness.
- Cholinesterase inhibition.

Source for Group Symptoms: Recognition and Management of Pesticide Poisoning, 5th edition, U.S. EPA, Chapter 4.

Treatment for Organophosphorus Poisoning

See: Recognition and Management of Pesticide Poisoning, 5th edition, U.S. EPA, Chapter 4, page 40.

 
 

Toxicity Information for Chlorpyrifos-methyl

  Note: Information for many chemicals is incomplete and may not be fully representative of effects on humans. Why?

Summary Toxicity Information

PAN Bad Actor
Chemical
1
Acute
Toxicity
2
Carcinogen Cholinesterase
Inhibitor
Ground
Water Contaminant
Developmental or
Reproductive Toxin
Endocrine
Disruptor
Not Acutely Toxic Not Likely
 
Indicates high toxicity in the given toxicological category. Indicates no available weight-of-the-evidence summary assessment. For additional information on toxicity from scientific journals or registration documents, see the "Additional Resources for Toxicity " section of the chemical detail page.
1. PAN Bad Actors are chemicals that are one or more of the following: highly acutely toxic, cholinesterase inhibitor, known/probable carcinogen, known groundwater pollutant or known reproductive or developmental toxicant. NOTE! Because there are no authoritative lists of Endocrine Disrupting (ED) chemicals, EDs are not yet considered PAN Bad Actor chemicals.
2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.

Detailed Toxicity Information

This Chemical
Parent Chemical 
Acute Toxicity 2
Chlorpyrifos-methyl Chlorpyrifos
WHO Acute Hazard
TRI Acute Hazard
Material Safety Data Sheets
Acute rating from U.S. EPA product label
U.S. NTP Acute Toxicity Studies
      View Studies
Cholinesterase Inhibitor
U, Unlikely to be Hazardous
Not Listed
Not Available
No Consensus Value
No NTP Studies

Yes
II, Moderately Hazardous
Not Listed
Not Available
Moderately Toxic
Slightly to Moderately Toxic

Yes
2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.
 
Cancer Information
Chlorpyrifos-methyl Chlorpyrifos
IARC Carcinogens
U.S. NTP Carcinogens
California Prop 65 Known Carcinogens
U.S. EPA Carcinogens
TRI Carcinogen
Not Listed
Not Listed
Not Listed
Not Likely
Not Listed
Not Listed
Not Listed
Not Listed
E, Unlikely
Not Listed
 
Endocrine Disruption
Chlorpyrifos-methyl Chlorpyrifos
Illinois EPA list
Keith list
Colborn list
Benbrook list
Danish Inert list
EU list
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Yes
Not Listed
Yes
Not listed
Yes
 
Reproductive and Developmental Toxicity
Chlorpyrifos-methyl Chlorpyrifos
CA Prop 65 Developmental Toxin
U.S. TRI Developmental Toxin
CA Prop 65 Female Reproductive Toxin
CA Prop 65 Male Reproductive Toxin
U.S. TRI Reproductive Toxin
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
 
Chemicals of Special Concern
Chlorpyrifos-methyl Chlorpyrifos
PAN Bad Actors
PAN Dirty Dozen list
Yes
Not Listed
Yes
Not Listed
 

Water Pollution Potential and Criteria for Chlorpyrifos-methyl

Water Pollution Potential

This Chemical
Parent Chemical
  Chlorpyrifos-methyl Chlorpyrifos
PAN Ground Water Contaminant Rating Insufficient Data Insufficient Data
 
Physical Property Data Related to Water Contamination Potential
Water Solubility (Avg, mg/L)
Adsorption Coefficient (Koc)
Hydrolysis Half-life (Avg, Days)
Aerobic Soil Half-life (Avg, Days)
Anaerobic Soil Half-life (Avg, Days)
2.74
4,645
21.0
3.00
-
 
 

Sorry, no water quality standards or criteria have been established for this chemical by the U.S. or Canadian governments; however, there may be criteria established for related chemicals.

 

Regulatory Information for Chlorpyrifos-methyl

International Regulatory Status

This Chemical
Parent Chemical 
 
UNEP Persistent Organic Pollutant (POP)
UNEP Prior Informed Consent Chemical (PIC)
WHO Obsolete Pesticide
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
 

U.S. and California Regulatory Status

U.S. EPA Registered
U.S. EPA Hazardous Air Pollutant
U.S. EPA Minimum Risk Pesticide (25b list)

CA Registered
CA Groundwater Contaminant
CA Toxic Air Contaminant
Yes
Not Listed
No

No
Not Listed
Not Listed
Yes
Not Listed
No

Yes
Not Listed
In Evaluation
 

Maximum Tolerance and Residue Levels

Codex Alimentarius
   (UN FAO Maximum Residue Limits)
U.S. Maximum Tolerance Levels
European Union Maximum Residue Levels
Go to web site

Go to web site

Go to web site
 

Ecotoxicity for Chlorpyrifos-methyl

Note! Information for many chemicals is incomplete and may not be fully representative of effects on the environment. Why? Click on underlined terms for definitions and additional information.

Aquatic Ecotoxicity

All Toxic Effects for Organism Group
Organism Group Effects Noted
Amphibians Behavior, Mortality
Cnidaria Mortality
Crustaceans Mortality, No Effect Coded
Fish Accumulation, Behavior, Mortality
Insects Mortality, Population
Molluscs Accumulation, Biochemistry, Enzyme(s), Intoxication, Morphology, Mortality, Physiology
Zooplankton Enzyme(s), Intoxication, Mortality, Population
~ Un-Assigned Mortality
View All Aquatic Ecotoxicity Studies and References
 
Summary of Acute Toxicity for Organism Group
Organism Group Average Acute Toxicity Acute Toxicity Range
Amphibians Moderately Toxic Moderate Toxicity
Crustaceans Very Highly Toxic Very Highly Toxic
Fish Moderately Toxic Moderate to High Toxicity
Insects Very Highly Toxic Very Highly Toxic
Zooplankton Moderately Toxic Moderate to Very High Toxicity
~ Un-Assigned Very Highly Toxic Very Highly Toxic
View All Acute Summaries
 

Terrestrial Ecotoxicity

Summary of Acute Toxicity for Organism Group
Organism Group Average Acute Toxicity Acute Toxicity Range
HoneybeesHighly ToxicHighly Toxic
Note: Population-level effects on honeybees may occur even if a pesticide has low acute toxicity. For example, certain pesticides interfere with honeybee reproduction, ability to navigate, or temperature regulation, any of which can have an effect on long-term survival of honeybee colonies. The neonicotinoids, pyrethroids and keto-enol pesticides are some types of pesticides causing one or more of these effects.
Honeybee Chronic Toxicity

Sorry, no honeybee chronic toxicity data available for this chemical. Try related chemicals.

Related Chemicals for Chlorpyrifos-methyl

CAS Number Relation Reason Chemical Name Chem Detail Symptoms California Use Chem Use Type U.S. EPA Reg PAN Bad Actor
2921-88-2 Parent P Chlorpyrifos View View View Insecticide, Nematicide Yes Yes
6515-38-4 Related 5a 3,5,6-Trichloro-2-pyridinol View View View Breakdown product No Not Listed
Related 5b Chlorpyrifos methyl oxygen analog View View View Breakdown product No Yes
5598-15-2 Related 5b Chlorpyrifos oxygen analog View View View Insecticide, Breakdown product No Yes
5598-13-0, 5998-13-0 Related 2 Chlorpyrifos-methyl View View View Insecticide Yes Yes
 
Working with the Information on this Page

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* Data marked with an asterisk indicates that this chemical is not explicitly listed on the corresponding list. Instead, it belongs to a group of chemicals that IS designated on the list. For example, if an agency assigns a classification of reproductive toxicant to "mercury compounds", that classification is applied to all mercury compounds in the PAN Pesticide database, which are then marked with an asterisk.

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