PAN Pesticides Database - Chemicals

Clothianidin - Identification, toxicity, use, water pollution potential, ecological toxicity and regulatory information

Note: See Working with the Information on this Page section below for important notes about this data.

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Identifying information, including synonyms, ID numbers, use type, chemical classification, a link to a list of all products containing this chemical and a list of the top crops this pesticide is used on in California.
Signs and symptoms of poisoning, first aid, and links to treatment information for this chemical.
Link to information on toxicity to humans, including carcinogenicity, reproductive and developmental toxicity, neurotoxicity, and acute toxicity.
Links to world-wide registration status as well as regulatory information for the U.S. and California.
Water quality standards and physical properties affecting water contamination potential.
Toxicity to aquatic organisms.
List of chemicals in the same family, including breakdown products, salts, esters, isomers, and other derivatives.
 

Chemical Identification and Use for Clothianidin

Basic Identification Information About This Chemical
Chemical Name: Clothianidin
CAS Number: 205510-53-8 (stereochemistry unspecified)
210880-92-5 (E-isomer)
205510-92-5
131748-59-9
U.S. EPA PC Code: 044309 (stereochemistry unspecified)
660108 (E-isomer)
CA DPR Chem Code: 5792
Molecular Weight: 249.68
Molecular Structure:
Use Type: Insecticide
Chem Class: Neonicotinoid
View Related Chemicals
 
Additional Resources About This Chemical Class and Use Type
Historical Use of this Chemical
Top five crops and sites for this pesticide in California
Cotton   Table and Raisin Grapes   Almonds   Wine Grapes   Walnuts  
View All Crops and Sites
 
Other Names for this Chemical
About Chemical Synonyms
(US EPA PC Code (stereochemistry unspecified)) , (US EPA PC Code (stereochemistry unspecified)) , (E)-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine , 044309 (US EPA PC Code Text (stereochemistry unspecified)) , 1-(2-Chloro-5-thiazolylmethyl)-3-methyl-2-nitroguanidine , 131748-59-9 (CAS number) , 131748599 (CAS number without hyphens) , 205510-53-8 (CAS number) , 205510-92-5 (CAS number) , 205510538 , 205510538 (CAS number without hyphens) , 205510925 (CAS number without hyphens) , 210880-92-5 (CAS number) , 210880925 (CAS number without hyphens) , 5792 (CA DPR Chem Code) ) , 660108 (US EPA PC Code Text (stereochemistry unspecified)) , AEP (PDP Code) , CGA 322704 , CGA322704 , Chlothianidin , Clothianidin , CLOTHIANIDIN (CA DPR Chem Code Text ) , Clothianidin(MNG metabolite) , Clothianidin(TMG metabolite) , Clothianidin(TZMU metabolite) , clothianidine , Clotianidina , Guanidine, N-(2-chloro-5-thiazolyl)methyl-N'-methyl-N''-nitro-,(E)- (9CI) (CA INDEX NAME) , Guanidine, N-(2-chloro-5-thiazolyl)methyl , Guanidine, N-[(2-chloro-5-thiazolyl)methyl]-N'-methyl-N''-nitro- , Guanidine, N-[(2-chloro-5-thiazolyl)methyl]-N'-methyl-N''-nitro-, [C(E)]- , N-[(2-chloro-1,3-thiazol-5-yl)methyl]-N'-methyl-N''-nitroguanidine , Thiamethoxam breakdown product , TI 435 , [C(E)]-N-[(2-Chloro-5-thiazolyl)methyl]-N'-methyl-N''-nitroguanidine
 
Products Containing This Chemical
Current and historic U.S. registered products
View U.S. Products All Products Currently Registered Products
 

Signs and Symptoms of Clothianidin Poisoning

NOTE! There may be other diseases and chemicals that have similar symptoms.

If you have a poisoning emergency in the United States call 1-800-222-1222.
If the victim has collapsed or is unconscious, call 911.

Sorry! No symptoms for this chemical or chemical group are available. See related chemicals for possible additional information.

 
 

Toxicity Information for Clothianidin

  Note: Information for many chemicals is incomplete and may not be fully representative of effects on humans. Why?

Summary Toxicity Information

PAN Bad Actor
Chemical
1
Acute
Toxicity
2
Carcinogen Cholinesterase
Inhibitor
Ground
Water Contaminant
Developmental or
Reproductive Toxin
Endocrine
Disruptor
Not Listed
Not Likely No Potential
 
Indicates high toxicity in the given toxicological category. Indicates no available weight-of-the-evidence summary assessment. For additional information on toxicity from scientific journals or registration documents, see the "Additional Resources for Toxicity " section of the chemical detail page.
1. PAN Bad Actors are chemicals that are one or more of the following: highly acutely toxic, cholinesterase inhibitor, known/probable carcinogen, known groundwater pollutant or known reproductive or developmental toxicant. NOTE! Because there are no authoritative lists of Endocrine Disrupting (ED) chemicals, EDs are not yet considered PAN Bad Actor chemicals.
2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.

Detailed Toxicity Information

This Chemical
Parent Chemical 
Acute Toxicity 2
Clothianidin Thiamethoxam
WHO Acute Hazard
TRI Acute Hazard
Material Safety Data Sheets
Acute rating from U.S. EPA product label
U.S. NTP Acute Toxicity Studies
      View Studies
Cholinesterase Inhibitor
Not Listed
Not Listed
Not Available
No Consensus Value
No NTP Studies

No
Not Listed
Not Listed
Not Available
No Consensus Value
No NTP Studies

No
2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.
 
Cancer Information
Clothianidin Thiamethoxam
IARC Carcinogens
U.S. NTP Carcinogens
California Prop 65 Known Carcinogens
U.S. EPA Carcinogens
TRI Carcinogen
Not Listed
Not Listed
Not Listed
Not Likely
Not Listed
Not Listed
Not Listed
Not Listed
Not Likely
Not Listed
 
Endocrine Disruption
Clothianidin Thiamethoxam
Illinois EPA list
Keith list
Colborn list
Benbrook list
Danish Inert list
EU list
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
 
Reproductive and Developmental Toxicity
Clothianidin Thiamethoxam
CA Prop 65 Developmental Toxin
U.S. TRI Developmental Toxin
CA Prop 65 Female Reproductive Toxin
CA Prop 65 Male Reproductive Toxin
U.S. TRI Reproductive Toxin
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
 
Chemicals of Special Concern
Clothianidin Thiamethoxam
PAN Bad Actors
PAN Dirty Dozen list
Not Listed
Not Listed
Not Listed
Not Listed
 

Water Pollution Potential and Criteria for Clothianidin

Water Pollution Potential

This Chemical
Parent Chemical
  Clothianidin Thiamethoxam
PAN Ground Water Contaminant Rating Potential Potential
 
Physical Property Data Related to Water Contamination Potential
Water Solubility (Avg, mg/L)
Adsorption Coefficient (Koc)
Hydrolysis Half-life (Avg, Days)
Aerobic Soil Half-life (Avg, Days)
Anaerobic Soil Half-life (Avg, Days)
259.0
160.0
33.0
214.0
27.0
 
 

Sorry, no water quality standards or criteria have been established for this chemical by the U.S. or Canadian governments; however, there may be criteria established for related chemicals.

 

Regulatory Information for Clothianidin

International Regulatory Status

This Chemical
Parent Chemical 
 
UNEP Persistent Organic Pollutant (POP)
UNEP Prior Informed Consent Chemical (PIC)
WHO Obsolete Pesticide
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
 

U.S. and California Regulatory Status

U.S. EPA Registered
U.S. EPA Hazardous Air Pollutant
U.S. EPA Minimum Risk Pesticide (25b list)

CA Registered
CA Groundwater Contaminant
CA Toxic Air Contaminant
Yes
Not Listed
No

Yes
Not Listed
Not Listed
Yes
Not Listed
No

Yes
Potential
Not Listed
 

Maximum Tolerance and Residue Levels

Codex Alimentarius
   (UN FAO Maximum Residue Limits)
U.S. Maximum Tolerance Levels
European Union Maximum Residue Levels
Go to web site

Go to web site

Go to web site
 

Ecotoxicity for Clothianidin

Note! Information for many chemicals is incomplete and may not be fully representative of effects on the environment. Why? Click on underlined terms for definitions and additional information.

Aquatic Ecotoxicity

All Toxic Effects for Organism Group
Organism Group Effects Noted
Crustaceans Mortality
View All Aquatic Ecotoxicity Studies and References
 
Summary of Acute Toxicity for Organism Group

Sorry, no acute aquatic ecotoxicity data available for this chemical. Try related chemicals.

 

Terrestrial Ecotoxicity

Summary of Acute Toxicity for Organism Group
Organism Group Average Acute Toxicity Acute Toxicity Range
HoneybeesSlightly ToxicNot AcutelyT to Highly Toxic
Note: Population-level effects on honeybees may occur even if a pesticide has low acute toxicity. For example, certain pesticides interfere with honeybee reproduction, ability to navigate, or temperature regulation, any of which can have an effect on long-term survival of honeybee colonies. The neonicotinoids, pyrethroids and keto-enol pesticides are some types of pesticides causing one or more of these effects.
Honeybee Chronic Toxicity
Organism Group Chronic Toxicity  
HoneybeesYes  

Related Chemicals for Clothianidin

CAS Number Relation Reason Chemical Name Chem Detail Symptoms California Use Chem Use Type U.S. EPA Reg PAN Bad Actor
153719-23-4 Parent P Thiamethoxam View View View Insecticide Yes Not Listed
205510-53-8, 210880-92-5, 205510-92-5, 131748-59-9 Related 2 Clothianidin View View View Insecticide Yes Not Listed
 
Working with the Information on this Page

Click on underlined terms for definitions or go to the Pesticide Tutorial overview page.

Any underlined term with a book icon has additional information.

* Data marked with an asterisk indicates that this chemical is not explicitly listed on the corresponding list. Instead, it belongs to a group of chemicals that IS designated on the list. For example, if an agency assigns a classification of reproductive toxicant to "mercury compounds", that classification is applied to all mercury compounds in the PAN Pesticide database, which are then marked with an asterisk.

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