PAN Pesticides Database - Chemicals

Azinphos-methyl - Identification, toxicity, use, water pollution potential, ecological toxicity and regulatory information

Note: See Working with the Information on this Page section below for important notes about this data.

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Identifying information, including synonyms, ID numbers, use type, chemical classification, a link to a list of all products containing this chemical and a list of the top crops this pesticide is used on in California.
Signs and symptoms of poisoning, first aid, and links to treatment information for this chemical.
Link to information on toxicity to humans, including carcinogenicity, reproductive and developmental toxicity, neurotoxicity, and acute toxicity.
Links to world-wide registration status as well as regulatory information for the U.S. and California.
Water quality standards and physical properties affecting water contamination potential.
Toxicity to aquatic organisms.
List of chemicals in the same family, including breakdown products, salts, esters, isomers, and other derivatives.

Chemical Identification and Use for Azinphos-methyl

Basic Identification Information About This Chemical
Chemical Name: Azinphos-methyl
CAS Number: 86-50-0
U.S. EPA PC Code: 058001
CA DPR Chem Code: 314
Molecular Weight: 317.32
Use Type: Insecticide
Chem Class: Organophosphorus
View Related Chemicals
Additional Resources About This Chemical Class and Use Type
Other Names for this Chemical
About Chemical Synonyms
00314 (CA DPR Chem Code Text ) , 042 (PDP Code) , 058001 [US EPA PC Code, Text ] , 314 (CA DPR Chem Code) ) , 58001 [US EPA PC Code, Numeric ] , 86-50-0 (CAS number) , 86500 , 86500 (CAS number without hyphens) , azinfos methyl , azinfos-methyl , Azinfos-metilo , azinfosmethyl , azinfosmetyl , Azinphos methyl , Azinphos, methyl , Azinphos-methyl , Azinphos-methyl (Guthion) , Azinphosmethyl , Bay 17147 , Bay 9027 , Carfene , Cotnion-Methyl , Crysthyon 2L , DBD , Dimethoxy ester of (4-oxo-1,2,3-benzotriazin-3(4H)-yl)methyl ester of dithiophosphoric acid , Dimethyldithiophosphoric acid, N-methylbenzazimide ester , ENT 23,233 , Gusathion , Gusathion M , Gusathion methyl , Guthion , Methyl azinphos , Methyl gusathion , Methyl guthion , Metilazinfosz , O,O-Dimethyl S-((4-oxo-1,2,3-benzotriazin-3(4H)-yl)methyl) phosphorodithioate , O,O-Dimethyl S-(3-(mercaptomethyl)-1,2,3-benzotriazin-4(3H)-one) phosphorodithioate , O,O-Dimethyl S-[(4-oxo-1,2,3-benzotriazin-3(4H)-yl)methyl] ester, Phosphorodithioic acid , Phosphorodithioic acid, O,O-dimethyl ester, S-ester with 3-(mercaptomethyl)-1,2,3-benzotriazin-4(3H)-one , Phosphorodithioic acid, O,O-dimethyl S-((4-oxo-1,2,3-benzotriazin-3(4H)-yl)methyl) ester , R 1582
Products Containing This Chemical
Current and historic U.S. registered products
View U.S. Products All Products Currently Registered Products

Signs and Symptoms of Azinphos-methyl Poisoning

NOTE! There may be other diseases and chemicals that have similar symptoms.

If you have a poisoning emergency in the United States call 1-800-222-1222.
If the victim has collapsed or is unconscious, call 911.

Azinphos-methyl is a Organophosphorus compound.

Report a Poisoning

Symptoms of Poisoning with Organophosphorus Compounds
Find Products Containing this Chemical

- Excessive salivation, sweating, rhinorrhea and tearing.
- Muscle twitching, weakness, tremor, incoordination.
- Headache, dizziness, nausea, vomiting, abdominal cramps, diarrhea.
- Respiratory depression, tightness in chest, wheezing, productive cough, fluid in lungs.
- Pin-point pupils, sometimes with blurred or dark vision.
- Severe cases: seizures, incontinence, respiratory depression, loss of consciousness.
- Cholinesterase inhibition.

Source for Group Symptoms: Recognition and Management of Pesticide Poisoning, 5th edition, U.S. EPA, Chapter 4.

Treatment for Organophosphorus Poisoning

See: Recognition and Management of Pesticide Poisoning, 5th edition, U.S. EPA, Chapter 4, page 40.

Symptoms of Azinphos-methyl Exposure from the International Chemical Safety Cards (ICSC)

Report a Poisoning

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Route of Exposure


First Aid

Inhalation Convulsions. Dizziness. Headache. Sweating. Laboured breathing. Nausea. Unconsciousness. Pupillary constriction muscle cramp excessive salivation. Wheezing. Fresh air rest. Artificial respiration if indicated. Refer for medical attention.
Skin MAY BE ABSORBED! (See Inhalation). Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.
Eyes Blurred vision. First rinse with plenty of water for several minutes (remove contact lenses if easily possible) then take to a doctor.
Ingestion Abdominal cramps. Diarrhoea. Vomiting. Blurred vision. (Further see Inhalation). Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Notes for ICSC Information
The technical material is a brown waxy solid. Depending on the degree of exposure periodic medical examination is indicated. The symptoms of acute intoxication do not become manifest until 30 minutes to 1-2 hours. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. If the substance is formulated with solvent(s) also consult the card(s) (ICSC) of the solvent(s). Carrier solvents used in commercial formulations may change physical and toxicological properties. Do NOT take working clothes home. Guthion and Gusathion M are trade names.

Toxicity Information for Azinphos-methyl

  Note: Information for many chemicals is incomplete and may not be fully representative of effects on humans. Why?

Summary Toxicity Information

PAN Bad Actor
Carcinogen Cholinesterase
Water Contaminant
Developmental or
Reproductive Toxin
Not Likely
Indicates high toxicity in the given toxicological category. Indicates no available weight-of-the-evidence summary assessment. For additional information on toxicity from scientific journals or registration documents, see the "Additional Resources for Toxicity " section of the chemical detail page.
1. PAN Bad Actors are chemicals that are one or more of the following: highly acutely toxic, cholinesterase inhibitor, known/probable carcinogen, known groundwater pollutant or known reproductive or developmental toxicant. NOTE! Because there are no authoritative lists of Endocrine Disrupting (ED) chemicals, EDs are not yet considered PAN Bad Actor chemicals.
2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.

Detailed Toxicity Information

Acute Toxicity 2
WHO Acute Hazard
TRI Acute Hazard
Material Safety Data Sheets
Acute rating from U.S. EPA product label
U.S. NTP Acute Toxicity Studies
      View Studies
Cholinesterase Inhibitor
Ib, Highly Hazardous
Not Listed
Not Available
Highly Toxic
Moderately to Highly Toxic

2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.
Cancer Information
IARC Carcinogens
U.S. NTP Carcinogens
California Prop 65 Known Carcinogens
U.S. EPA Carcinogens
TRI Carcinogen
Not Listed
Not Listed
Not Listed
Not Likely
Not Listed
Endocrine Disruption
Illinois EPA list
Keith list
Colborn list
Benbrook list
Danish Inert list
EU list

Reproductive and Developmental Toxicity
CA Prop 65 Developmental Toxin
U.S. TRI Developmental Toxin
CA Prop 65 Female Reproductive Toxin
CA Prop 65 Male Reproductive Toxin
U.S. TRI Reproductive Toxin
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Chemicals of Special Concern
PAN Bad Actors
PAN Dirty Dozen list
Not Listed

Water Pollution Potential and Criteria for Azinphos-methyl

Water Pollution Potential

PAN Ground Water Contaminant Rating Potential
Physical Property Data Related to Water Contamination Potential
Water Solubility (Avg, mg/L)
Adsorption Coefficient (Koc)
Hydrolysis Half-life (Avg, Days)
Aerobic Soil Half-life (Avg, Days)
Anaerobic Soil Half-life (Avg, Days)

Water Standards and Criteria

Canada Drinking Water Standards and Criteria
g/L unless noted  
Maximum Acceptable Concentration (MAC) 20.0
Interim Maximum Acceptable Concentration (IMAC)
Aesthetic Objectives

Regulatory Information for Azinphos-methyl

International Regulatory Status

UNEP Persistent Organic Pollutant (POP)
UNEP Prior Informed Consent Chemical (PIC)
WHO Obsolete Pesticide
Not Listed
Not Listed
Not Listed

U.S. and California Regulatory Status

U.S. EPA Registered
U.S. EPA Hazardous Air Pollutant
U.S. EPA Minimum Risk Pesticide (25b list)

CA Registered
CA Groundwater Contaminant
CA Toxic Air Contaminant
Not Listed

In Evaluation

Maximum Tolerance and Residue Levels

Codex Alimentarius
   (UN FAO Maximum Residue Limits)
U.S. Maximum Tolerance Levels
European Union Maximum Residue Levels
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Ecotoxicity for Azinphos-methyl

Note! Information for many chemicals is incomplete and may not be fully representative of effects on the environment. Why? Click on underlined terms for definitions and additional information.

Aquatic Ecotoxicity

All Toxic Effects for Organism Group
Organism Group Effects Noted
Amphibians Biochemistry, Development, Enzyme(s), Growth, Injury, Morphology, Mortality, Physiology, Population
Annelida Behavior, Biochemistry, Enzyme(s), Mortality
Crustaceans Behavior, Development, Enzyme(s), Growth, Histology, Mortality, No Effect Coded, Physiology, Population
Fish Accumulation, Avoidance, Behavior, Biochemistry, Development, Enzyme(s), Genetics, Growth, Morphology, Mortality, Physiology, Population, Reproduction
Insects Behavior, Development, Enzyme(s), Intoxication, Mortality, Population
Molluscs Behavior, Biochemistry, Development, Enzyme(s), Growth, Intoxication, Morphology, Mortality, Population
NematodesandFlatworms Mortality, Population
Phytoplankton Biochemistry, Ecosystem Process, Physiology, Population
Zooplankton Development, Enzyme(s), Growth, Intoxication, Mortality, Physiology, Population, Reproduction
~ Un-Assigned Development, Enzyme(s), Mortality, Population
~Un-Assigned Population
View All Aquatic Ecotoxicity Studies and References
Summary of Acute Toxicity for Organism Group
Organism Group Average Acute Toxicity Acute Toxicity Range
Amphibians Moderately Toxic Moderate to High Toxicity
Annelida Highly Toxic Highly Toxic
Crustaceans Very Highly Toxic High to Very High Toxicity
Fish Highly Toxic Moderate to Very High Toxicity
Insects Very Highly Toxic Very Highly Toxic
Molluscs Moderately Toxic Slight to High Toxicity
NematodesandFlatworms Highly Toxic Highly Toxic
Zooplankton Moderately Toxic Slight to Very High Toxicity
~ Un-Assigned Highly Toxic Moderate to Very High Toxicity
View All Acute Summaries

Terrestrial Ecotoxicity

Summary of Acute Toxicity for Organism Group
Organism Group Average Acute Toxicity Acute Toxicity Range
HoneybeesModerately ToxicModerately to Highly Toxic
Note: Population-level effects on honeybees may occur even if a pesticide has low acute toxicity. For example, certain pesticides interfere with honeybee reproduction, ability to navigate, or temperature regulation, any of which can have an effect on long-term survival of honeybee colonies. The neonicotinoids, pyrethroids and keto-enol pesticides are some types of pesticides causing one or more of these effects.
Honeybee Chronic Toxicity
Organism Group Chronic Toxicity  

Related Chemicals for Azinphos-methyl

CAS Number Relation Reason Chemical Name Chem Detail Symptoms California Use Chem Use Type U.S. EPA Reg PAN Bad Actor
86-50-0 Parent P Azinphos-methyl View View View Insecticide No Yes
Related 5b Azinphos-methyl oxygen analog View View View Breakdown product No Yes
Working with the Information on this Page

Click on underlined terms for definitions or go to the Pesticide Tutorial overview page.

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* Data marked with an asterisk indicates that this chemical is not explicitly listed on the corresponding list. Instead, it belongs to a group of chemicals that IS designated on the list. For example, if an agency assigns a classification of reproductive toxicant to "mercury compounds", that classification is applied to all mercury compounds in the PAN Pesticide database, which are then marked with an asterisk.

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