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Pesticide Info

2-methyl-4-isothiazolin-3-one

Summary

Chemical name
2-methyl-4-isothiazolin-3-one
EPA PC code
107104
CAS number
2682-20-4
CA DPR chem code
2039
Chemical class
Isothiazolone
Molecular weight
115.15
Use type
Microbiocide
EPA Registered
Yes
PAN Bad Actor
PAN created the term PAN Bad Actor for pesticides that are carcinogenic, reproductive or developmental toxicants, cholinesterase inhibitors, groundwater contaminants and/or have high acute toxicity. Read more
Not Listed
Highly Hazardous Pesticide
PAN International maintains a list of Highly Hazardous Pesticides (HHPs) that are classified by recognized authorities as highly hazardous to human health and/or the environment. Read more
Not Listed
Drift Prone (VP)
Not Listed

Toxicity of 2-methyl-4-isothiazolin-3-one

Acute Toxicity
Acute toxicity refers to the immediate effects (0-7 days) of exposure to a pesticide. Highly acutely toxic pesticides can be lethal at very low doses. Read more
Insufficiently Studied
Endocrine Disruptor
Insufficiently Studied
Cholinesterase Inhibitor
No
CA Groundwater Contaminant
Insufficient data
Carcinogen
Insufficiently Studied
Bee Toxicant
EPA maintains a list of pesticides considered highly toxic to bees, and these pesticides are also included in the PAN HHP List. Read more
Not Listed
Reproductive and Developmental Toxicant
Some pesticides cause reproductive and developmental harm, which can include birth defects, infertility, sterility and impairment of normal growth and development. Read more
Insufficiently Studied

Other Names for 2-methyl-4-isothiazolin-3-one

02039 (CA DPR Chem Code Text )
107104 [US EPA PC Code, Numeric ]
107104 [US EPA PC Code, Text ]
2-Methyl-3-isothiazolone
2-Methyl-3(2H)-isothiazolone
2-methyl-4-isothiazolin-3-one
2-Methylisothiazol-3-one
2039 (CA DPR Chem Code) )

Toxicity of 2-methyl-4-isothiazolin-3-one

Acute Toxicity
Acute toxicity refers to the immediate effects (0-7 days) of exposure to a pesticide. Highly acutely toxic pesticides can be lethal at very low doses. Read more
Insufficiently Studied
Reproductive and Developmental Toxicant
Some pesticides cause reproductive and developmental harm, which can include birth defects, infertility, sterility and impairment of normal growth and development. Read more
Insufficiently Studied
Cholinesterase Inhibitor
Some pesticides inhibit the enzyme cholinesterase, which is essential for transmission of nerve impulses. Read more
No
Endocrine Disruption
Many pesticides can interfere with proper functioning of estrogen, androgen and thyroid hormones in humans and animals. Read more
Insufficiently Studied
Carcinogen
Several organizations evaluate and rank chemicals for their cancer-causing potential. PAN's summary listing reflects the most toxic ranking assigned. Read more
Insufficiently Studied

Reproductive & Developmental Toxicity

California Prop 65 Developmental Toxicant
Not Listed
CA Prop 65 Male Reproductive Toxicant
Not Listed
U.S. TRI Developmental Toxicant
Not Listed
U.S. TRI Reproductive Toxicant
Not Listed
CA Prop 65 Female Reproductive Toxicant
Not Listed

Cancer Information

CA Prop 65 Known Carcinogens
Not Listed
TRI Carcinogen
Not Listed
IARC Carcinogens
Not Listed
Global Harmonized System
Not Listed
U.S. NTP Carcinogens
Not Listed
Mutagenic
Not Listed

Endocrine Disruption

EU ED Rating
Insufficiently Studied

2-methyl-4-isothiazolin-3-one POISONING: SIGNS & SYMPTOMS

Summary signs & symptoms for chemical:
Summary signs & symptoms group:
Not Listed
Treatment:
Not Listed

Symptoms of Exposure from the International Chemical Safety Card:

Route of Exposure Symptoms First Aid
Inhalation No Data No Data
Skin No Data No Data
Eyes No Data No Data
Ingestion No Data No Data

Environmental Toxicity

For in-depth information on Ecotoxicity by Chemical, Species, and Effect, we encourage users to visit EPA's ECOTOX site which is updated regularly. We provide detailed, step-by-step search guidance on our Ecotoxicity Resources page, so users can more easily access and use EPA's site.

Water Contamination Potential

CA Groundwater Contaminant
Insufficient data
Aerobic Soil Half-life (Avg, Days)
Not Listed
Adsorption Coefficient (Koc)
Not Listed
Anaerobic Soil Half-life (Avg, Days)
Not Listed
Hydrolysis Half-life (Avg, Days)
Not Listed
Water solubility (mg/L)
Not Listed

U.S. National Drinking Water Standards

Lifetime Exposure Health Advisory Level (mg/L)
Not Listed
Maximum Contaminant Level Goal (mg/L)
Not Listed
Reference Dose (g/kg/day)
Not Listed
One Day Exposure Health Advisory Level (mg/L)
Not Listed
U.S. Drinking Water Equivalent Level (mg/L)
Not Listed
Ten Day Exposure Health Advisory Level (mg/L)
Not Listed
Concentration With Lifetime Cancer Risk (mg/L At 10-4)
Not Listed

PRODUCTS CONTAINING 2-methyl-4-isothiazolin-3-one (374 Results)

#95 microbiocide
1514
1560n
2120
2v-cide
3862
3884
6002
6962
7165 microbiocide
A - 263
A-482
A102
Aa-4015p
Aa4015
ab 986
Ab-1.5
Ab-cpl-5
Additive pr
Additive ry
Aeroset water bath additive
Ag-481
Al-702
Al-7400
Al-818
Algaepak biocide packets
Alpha 535
Alpha 935
Ama-115
Ama-215
Ama-415
Ama-4950
Ama-915
Amco 659
Amerstat(r) 250 sp microbiocide
Amoco(r) wellaid 846
Anco microbicide 77
Apollo 4726
Aq-7423 microbiocide
Aquonics 433
Arch mold inhibitor k-18500
Arco 8915
As-590
Awc d-1151
Axchem ab-1.5
Axchem ab-cp1.5
B.i.o. blast 526
Backtron k-145
Baf-155
Bc 100 p
Bc 100 p-cf
Bc 100 wt
Bc 195
Bc 475
Bc8002z
Bcs 3024p
Bcs 3104
Bellchem 610
Bener 1500
Betz enchem 41-j8
Betz entec 368
Betz er-28
Betz gcp-980
Betz rx-68a
Bio blast 526
Bio-iso15
Bio/tec 055
Bio/tec 072
Bio/tec 076
Bio/tec 081
Bio/tec 082
Bio/tec 083
Bio/tec 090
Bio/tec 091
Bio/tec 093
Bio/tec 097
Bioban 2000
Bioban 2001
Bioban 425 antimicrobial
BIOBAN BTCM Antimicrobial
Bioban mt 20 antimicrobial
Biocide lx 15
Biocide lx 415
Biocide mc 68 mw
Biocide mc 68 wt
Biomax ex340
Biopac
Biosol 130
Biosolv
Biosperese 250 ed
Biosperse 250 ed
Biosperse 250 sp
Biosperse 250 wt
Biosperse(r) 250 sp microbiocide
Biotreat 8416
Bond 15
Burman technical services
Busan 1078c
Busan 1078s
C-992
Cal cide 4210
Calgon pb-15l
Calmac 081
Cb-1215
Cbt 232
Cc-320
Ccl 2058
Cesco act 5015a
Chem tech mbc 215
Chem treat 2150
Chemcide k15
Chemical treatment c-2155
Chemicide 902
Chemicide bio3fc
Chemquest 211 cl
Chemstone 7475
Chemtech 915
Chemtreat cl-2156
Chemtreat cl2155
Chemtreat ct-2015
Chemtreat pr-2151
Chemtreat pr-2159
Cleanwood mold inhibitor
Clow 3862
Clow 6962
Coolant saver k.
Corexit 7677 microbiocide
Corexit 7685 oil field microbiocide
Crypton 7423
Cs4555 microbiocide
Culligan m-1015
Cw-4100
Cwt biocide d
Dasco additive b 2860
Dasco additive b2862
Detco formula 41
Di chem 645
Di chem g106
Dichem g106
Dobercide 374-c
Dobercide 374-d
Duracool 6493
Durok7g
Durotex 5000
Eabm-052
Edc-485
Enchem 41-j8a
Fbs 015
Fennosan it15
Fleet-tech microbicide
Formula 3015
Formula 313
Formula 3900
Galaxy 4100
Garratt-callahan formula 313
Gcs 3215
Gcs 3216
Grotan k 1.5%
Grotan k 11.2%
H-500 microbiocide
H-510cf microbiocide
Hyde kc-1
Hyde kc-2
Hydrasense mzd ml-27
Hydrex 7313
Hydrex 7314
Hydrex 7315
Hydroco m-197
Ibx-2g papermill slimicide
Icq c-series water bath additive
Ics-8423 microbiocide
Imco imx 140
Inhibitor 4427
Inhibitor 4430
Ipc(tm) 8916
Isc 215
Iso wt 1.5%
Iso-cide
Iso-cide d
Iso-link 1.5
Iso-pak
Iso-trol
Isoklenz kt
Jm is-50
Johnson's knockout #2
Johnson's knockout #2 concentrate
K-170
K-bac-7015
Kathon (tm) edc1.5% biocide
Kathon 28 wt
Kathon 7g antimicrobial
Kathon 7tl antimicrobial
Kathon 886 mw
Kathon 886 mw 1.5%
Kathon 886f industrial microbicide
Kathon cf-2800 industrial microbicide
Kathon cf-400
Kathon cg/icp
Kathon cg/icp ii
Kathon cl industrial microbicide
Kathon cs-25 oilfield micro biocide
Kathon cs-30 oil field microbiocide
Kathon cs-35
Kathon ed
Kathon ed 1.5%
Kathon fp
Kathon fp 1.5
Kathon fp 1.5% industrial microbicide
Kathon icp iii eup antimicrobial
Kathon mwc
Kathon mwx
Kathon pfm
Kathon ps
Kathon tcp ii
Kathon tcp industrial microbicide
Kathon wt
Kathon wt 1.5%
Kathon wt 1.5% industrial microbicide
Kathon(tm) 7 granular mup antimicrobial
Kathon(tm) 7n antimicrobial
Kemco bio
Kemicide 250sp
Kito(r) 150
Klean kil
Koppers mold inhibitor k-18500
Koppers mold inhibitor k-2000
Kordek 50c industrial microbicide
Kordek 573f
Kordek 573t industrial microbiocide
Kordek mlx
Kordek mtc
Lester microbiocide - 76
Lf 7000
Lq 4412
Lubricide mw #1
Lucide gk-1
M-1015p
M1015
Magnacide 450
Magnicide 486
Mb-2151
Mb-440
Mb-gard 1.5
Mb-i1.5
Mbc 150 fp
Mbc 211
Mbc 216
Mbc 217
Mbc 231
Mbc 297
Mbc 315
Mbc 915
Mbc 986
Mbc-400
Meco microbiocide j-61
Meco microbiocide kat
Meco microbiocide kwtd
Mergal MIT Technical
Mergal mitz
Microbicide 77m
Microbicide pms
Microbicide yr
Microbiocide 102
Microbiocide 53
Microbiocide 53w
Microbiocide 76
Microcide 100
Microgard 501
Mitco cc-33l
Mitco cwb 4605
Mitco cwb-4600
Mitco cwb-4620
Mitco ro-15ol
Ml-27
Ml-28
Mogul 6480f
Mogul a-482
Mogul ag-480f
Mogul ag-481
Mogul ag-481f
Mogul pc1345
Mogul pc1346
Mold - ex h. e. 14
Mold inhibitor k-18500
Mold-ex h.e.
Mold-ex h.e. 14
Moldex 28
Momar aquatrol alg-400
Momar sump saver liquid concentrate 1.5%
Nalco 7330 industrial recirculating water cooling tower microbiocide
Nalco 77352
Nalco 77352na
Nalco 8wt506
Nalco duracool-mw
Nalcon 9pc-115
Neolone m-10
Nipacide cl 15
Nopcocide 26
Np-500
Nuosept (r) 515r
Nuosept(r) 515r ca
Olin 3305
Optima 18505
Osmose pressure treated wood mold inhibitor
Paper maker's slimicide
Paper-gard b-1.5
Papertex 8802l
Pennwalt lf 7000
Ppf mzd 7330
Ppf mzd 7360
Ppg mzd 7340
Preservacide 072
Proasys formula 1504
Proasys formula 1505
Pws formula 41
Quaker biocide 300
Quaker microbiocide 315
Rc 416
Rc+5 coolant controller
Robigus - wt 1.5%
Rocide-is2
Rocima (tm) 586
Rocima 550
Rocima 586
S-750
S-751
S-tec-35
Sapstain control booster
Sapstain control booster np-1 additive
Sapstsin control booster np-1 additive
Sc 6220
Schneider bio-gard
Schneider micro-cide 4 d
Schneider micro-cide 4 fs
Selcide 921
Selcide(tm) 901
Sf-886 technical industrial microbicide
Slime-trol dp-808
Slime-trol rx-68
Spec-aid 8q700
Spec-aid 8q701
Sump saver liquid concentrate
Supa k-886
Supatimber h.e. 14 wood mildewcide
Supatimber he 14
Supatimber mold inhibitor
Surflo b81w
Surflo-b81
Surflo-b812
Surflo-b81w
Tandemol inhibitol 6099
Tandemol inhibitor 6099
Tci-133
Ti-536b
Tmb 549
Tool-i-cide
Trim tc-173
Trim(r)tc-181
Troy 7474
Under-trol wt 1.5%
Val-u-add am
Van straaten conditioner no. 11
Van straaten conditioner no. 11a
Vaporene 7524 a
Veriguard 9
Veriguard 923
Wcs 102
West c-124 water treatment microbiocide
Wrico wra
Wtm-72
X-cell 426
X-cell 426 microbiocide
X-cide 211
X-cide 215
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Usage Map

US Pesticide Usage Map for 2-methyl-4-isothiazolin-3-one

Pesticide Usage Data

This map shows estimated agricultural usage of 2-methyl-4-isothiazolin-3-one across the United States.

View USGS Data

Data source: U.S. Geological Survey National Water-Quality Assessment Project

PRIMARY USE IN CALIFORNIA (6 Results)

Crop or Site Gross Pounds Application Rate (lbs a.i./acre) Acres Planted Acres Treated Application Count
All sites 36,909 0 0 0 37
LUMBER, TREATED 32,128 0 0 0 0
WATER INDUSTRIAL 4,213 0 0 0 0
INDUSTRIAL PROCESSING WATER 515 0 0 0 0
STRUCTURAL PEST CONTROL 46.6 0 0 0 36
WATER WASHER/COOLER/CONDENSER SYSTEMS 5.5 0 0 0 0
LANDSCAPE MAINTENANCE 0.5 0 0 0 1

Related Chemicals
PAN groups chemicals in our pesticide database based on their relationship to a parent compound. Read More

Chemical Name CAS Number Chem Use Type U.S. EPA Reg PAN Bad Actor
PAN created the term PAN Bad Actor for pesticides that are carcinogenic, reproductive or developmental toxicants, cholinesterase inhibitors, groundwater contaminants and/or have high acute toxicity. Read more
2-Methyl-3(2H)-isothiazolone, calcium chloride complex 57373-20-3 Microbiocide Not Listed Not Listed

International regulatory status

UNEP Persistent Organic Pollutant (POP)
A “POP” pesticide has been targeted for global phaseout under the Stockholm Convention for Persistent Organic Pollutants. Read more
Not Listed
UNEP Prior Informed Consent Chemical (PIC)
Not Listed
PAN International Ban List
PAN maintains a list of pesticides banned around the world, and the data are now available in an interactive map. Read more
No
EU Registered
No

Us regulatory status

U.S. EPA Registered
Yes
U.S. EPA Minimum Risk Pesticide (25b list)
No
U.S. EPA Hazardous Air Pollutant
Not Listed

California regulatory status

CA Registered
Yes
CA Toxic Air Contaminant
Not Listed
CA Groundwater Contaminant
Insufficient data

Allowable residue levels

Codex Alimentarius(UN FAO Maximum Residue Levels
European Union Maximum Residue level
U.S Maximum tolerance level