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Pesticide Info

2-methyl-4,5-trimethylene-4-isothiazolin-3-one

Poisoning Symptoms Report a Poisoning

Summary

Chemical name
2-methyl-4,5-trimethylene-4-isothiazolin-3-one
EPA PC code
107107
CAS number
82633-79-2
CA DPR chem code
5013
Chemical class
Isothiazolone
Molecular weight
Use type
Microbiocide
EPA Registered
No
PAN Bad Actor
PAN created the term PAN Bad Actor for pesticides that are carcinogenic, reproductive or developmental toxicants, cholinesterase inhibitors, groundwater contaminants and/or have high acute toxicity. Read more
Not Listed
Highly Hazardous Pesticide
PAN International maintains a list of Highly Hazardous Pesticides (HHPs) that are classified by recognized authorities as highly hazardous to human health and/or the environment. Read more
Not Listed
Drift Prone (VP)
Not Listed

Toxicity of 2-methyl-4,5-trimethylene-4-isothiazolin-3-one

Acute Toxicity
Acute toxicity refers to the immediate effects (0-7 days) of exposure to a pesticide. Highly acutely toxic pesticides can be lethal at very low doses. Read more
Insufficiently Studied
Endocrine Disruptor
Insufficiently Studied
Cholinesterase Inhibitor
No
CA Groundwater Contaminant
Insufficient data
Carcinogen
Insufficiently Studied
Bee Toxicant
EPA maintains a list of pesticides considered highly toxic to bees, and these pesticides are also included in the PAN HHP List. Read more
Not Listed
Reproductive and Developmental Toxicant
Some pesticides cause reproductive and developmental harm, which can include birth defects, infertility, sterility and impairment of normal growth and development. Read more
Insufficiently Studied

Other Names for 2-methyl-4,5-trimethylene-4-isothiazolin-3-one

05013 (CA DPR Chem Code Text )
107107 [US EPA PC Code, Numeric ]
107107 [US EPA PC Code, Text ]
2-methyl-4,5-trimethylene-4-isothiazolin-3-one
2-Methyl-5,6-dihydro-4H-cyclopenta(d) isothiazol-3-one
2-Methyl-5,6-dihydro-4H-cyclopenta(d) isothiazol-3-one (IUPAC NAME)
2H-Cyclopent(d)isothiazol-3(4H)-one, 5,6-dihydro-2-methyl-
2H-Cyclopent(d)isothiazol-3(4H)-one, 5,6-dihydro-2-methyl- (9CI)

Toxicity of 2-methyl-4,5-trimethylene-4-isothiazolin-3-one

Acute Toxicity
Acute toxicity refers to the immediate effects (0-7 days) of exposure to a pesticide. Highly acutely toxic pesticides can be lethal at very low doses. Read more
Insufficiently Studied
Reproductive and Developmental Toxicant
Some pesticides cause reproductive and developmental harm, which can include birth defects, infertility, sterility and impairment of normal growth and development. Read more
Insufficiently Studied
Cholinesterase Inhibitor
Some pesticides inhibit the enzyme cholinesterase, which is essential for transmission of nerve impulses. Read more
No
Endocrine Disruption
Many pesticides can interfere with proper functioning of estrogen, androgen and thyroid hormones in humans and animals. Read more
Insufficiently Studied
Carcinogen
Several organizations evaluate and rank chemicals for their cancer-causing potential. PAN's summary listing reflects the most toxic ranking assigned. Read more
Insufficiently Studied

Reproductive & Developmental Toxicity

California Prop 65 Developmental Toxicant
Not Listed
CA Prop 65 Male Reproductive Toxicant
Not Listed
U.S. TRI Developmental Toxicant
Not Listed
U.S. TRI Reproductive Toxicant
Not Listed
CA Prop 65 Female Reproductive Toxicant
Not Listed

Cancer Information

CA Prop 65 Known Carcinogens
Not Listed
TRI Carcinogen
Not Listed
IARC Carcinogens
Not Listed
Global Harmonized System
Not Listed
U.S. NTP Carcinogens
Not Listed
Mutagenic
Not Listed

Endocrine Disruption

EU ED Rating
Insufficiently Studied

2-methyl-4,5-trimethylene-4-isothiazolin-3-one POISONING: SIGNS & SYMPTOMS

Summary signs & symptoms for chemical:
Summary signs & symptoms group:
Not Listed
Treatment:
Not Listed

Symptoms of Exposure from the International Chemical Safety Card:

Route of Exposure Symptoms First Aid
Inhalation No Data No Data
Skin No Data No Data
Eyes No Data No Data
Ingestion No Data No Data

Environmental Toxicity

For in-depth information on Ecotoxicity by Chemical, Species, and Effect, we encourage users to visit EPA's ECOTOX site which is updated regularly. We provide detailed, step-by-step search guidance on our Ecotoxicity Resources page, so users can more easily access and use EPA's site.

Water Contamination Potential

CA Groundwater Contaminant
Insufficient data
Aerobic Soil Half-life (Avg, Days)
Not Listed
Adsorption Coefficient (Koc)
Not Listed
Anaerobic Soil Half-life (Avg, Days)
Not Listed
Hydrolysis Half-life (Avg, Days)
Not Listed
Water solubility (mg/L)
Not Listed

U.S. National Drinking Water Standards

Lifetime Exposure Health Advisory Level (mg/L)
Not Listed
Maximum Contaminant Level Goal (mg/L)
Not Listed
Reference Dose (g/kg/day)
Not Listed
One Day Exposure Health Advisory Level (mg/L)
Not Listed
U.S. Drinking Water Equivalent Level (mg/L)
Not Listed
Ten Day Exposure Health Advisory Level (mg/L)
Not Listed
Concentration With Lifetime Cancer Risk (mg/L At 10-4)
Not Listed

PRODUCTS CONTAINING 2-methyl-4,5-trimethylene-4-isothiazolin-3-one (2 Results)

Promexal x50 preservative
Silpure fbr-6 (part a)
No products match your search.

Usage Map

US Pesticide Usage Map for 2-methyl-4,5-trimethylene-4-isothiazolin-3-one

Pesticide Usage Data

This map shows estimated agricultural usage of 2-methyl-4,5-trimethylene-4-isothiazolin-3-one across the United States.

View USGS Data

Data source: U.S. Geological Survey National Water-Quality Assessment Project

PRIMARY USE IN CALIFORNIA

No Results Found!

Related Chemicals
PAN groups chemicals in our pesticide database based on their relationship to a parent compound. Read More

Chemical Name CAS Number Chem Use Type U.S. EPA Reg PAN Bad Actor
PAN created the term PAN Bad Actor for pesticides that are carcinogenic, reproductive or developmental toxicants, cholinesterase inhibitors, groundwater contaminants and/or have high acute toxicity. Read more
Kathon 886 (kathon biocide) 55965-84-9 Microbiocide Not Listed Not Listed
3(2H)-chloro-2-methyl-3(2H)-isothiazolone, calcium chloride complex 57373-19-0 Microbiocide Not Listed Not Listed
4,5-dichloro-2-n-octyl-3(2H)-isothiazolone 64359-81-5 Antifoulant, Microbiocide Yes Not Listed
5-chloro-2-methyl-4-isothiazolin-3-one 26172-55-4 Microbiocide Yes Not Listed
5-chloro-2-methyl-4-isothiazolin-3-one calcium chloride with 2-methyl-4-isothazolin-3-one calcium chloride 55965-87-2 Microbiocide Not Listed Not Listed

International regulatory status

UNEP Persistent Organic Pollutant (POP)
A “POP” pesticide has been targeted for global phaseout under the Stockholm Convention for Persistent Organic Pollutants. Read more
Not Listed
UNEP Prior Informed Consent Chemical (PIC)
Not Listed
PAN International Ban List
PAN maintains a list of pesticides banned around the world, and the data are now available in an interactive map. Read more
No
EU Registered
No

Us regulatory status

U.S. EPA Registered
No
U.S. EPA Minimum Risk Pesticide (25b list)
No
U.S. EPA Hazardous Air Pollutant
Not Listed

California regulatory status

CA Registered
No
CA Toxic Air Contaminant
Not Listed
CA Groundwater Contaminant
Insufficient data

Allowable residue levels

Codex Alimentarius(UN FAO Maximum Residue Levels
Visit Website
European Union Maximum Residue level
Visit Website
U.S Maximum tolerance level
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